ID A0A0F4PNQ9_9GAMM Unreviewed; 928 AA.
AC A0A0F4PNQ9;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CWC05_18100 {ECO:0000313|EMBL:TMP85546.1}, TW72_05635
GN {ECO:0000313|EMBL:KJZ00994.1};
OS Pseudoalteromonas ruthenica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Pseudoalteromonas.
OX NCBI_TaxID=151081 {ECO:0000313|EMBL:KJZ00994.1, ECO:0000313|Proteomes:UP000033664};
RN [1] {ECO:0000313|EMBL:KJZ00994.1, ECO:0000313|Proteomes:UP000033664}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S3137 {ECO:0000313|EMBL:KJZ00994.1,
RC ECO:0000313|Proteomes:UP000033664};
RX PubMed=25879706; DOI=10.1186/s12864-015-1365-z;
RA Machado H., Sonnenschein E.C., Melchiorsen J., Gram L.;
RT "Genome mining reveals unlocked bioactive potential of marine Gram-negative
RT bacteria.";
RL BMC Genomics 16:158-158(2015).
RN [2] {ECO:0000313|EMBL:TMP85546.1, ECO:0000313|Proteomes:UP000305874}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2897 {ECO:0000313|EMBL:TMP85546.1,
RC ECO:0000313|Proteomes:UP000305874};
RA Paulsen S., Gram L.K.;
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000305874}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2897 {ECO:0000313|Proteomes:UP000305874};
RA Sonnenschein E.C., Bech P.K.;
RT "Co-occurence of chitin degradation, pigmentation and bioactivity in marine
RT Pseudoalteromonas.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:TMP85546.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S2897 {ECO:0000313|EMBL:TMP85546.1};
RA Sonnenschein E.C., Bech P.K.;
RT "Co-occurence of chitin degradation, pigmentation and bioactivity in marine
RT Pseudoalteromonas.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJZ00994.1}.
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DR EMBL; JXXZ01000005; KJZ00994.1; -; Genomic_DNA.
DR EMBL; PNCG01000024; TMP85546.1; -; Genomic_DNA.
DR RefSeq; WP_045979501.1; NZ_PNCG01000024.1.
DR AlphaFoldDB; A0A0F4PNQ9; -.
DR STRING; 151081.TW72_05635; -.
DR GeneID; 58227971; -.
DR PATRIC; fig|151081.8.peg.2067; -.
DR eggNOG; COG2205; Bacteria.
DR OrthoDB; 9810730at2; -.
DR Proteomes; UP000033664; Unassembled WGS sequence.
DR Proteomes; UP000305874; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.20.120.160; HPT domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR036641; HPT_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR43719:SF28; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK2; 1.
DR PANTHER; PTHR43719; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF01627; Hpt; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF14938; SNAP; 1.
DR Pfam; PF13424; TPR_12; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47226; Histidine-containing phosphotransfer domain, HPT domain; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50894; HPT; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000033664};
KW Signal {ECO:0000256|SAM:SignalP};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..928
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5033221770"
FT TRANSMEM 418..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 140..173
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 220..253
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 480..697
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 719..833
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 843..928
FT /note="HPt"
FT /evidence="ECO:0000259|PROSITE:PS50894"
FT COILED 446..480
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 768
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 882
FT /note="Phosphohistidine"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00110"
SQ SEQUENCE 928 AA; 104346 MW; 323B77BC7E9D2C2A CRC64;
MSQRKLPRLL VCIQLLVCSL FTSLSYGDAL IDDIRSQPQQ LQRDYAISKL AQPLSEPQQL
AVNAFIAKQF FEDSNYEKAA RYYLRAEQLA AKHGTVIEHS RYAQMQGVSH YYRGQDLTAI
EDYLRAIEII EQIDKPIIAA HLYNNIGLAY SGADQIEAAI ASYSKAKELY DEYGDEYDQV
NIMHNIAVAY MDWYRFEAAF DIYEQIGDSF ERLGDTIGQA QMETNLGSIY QSRMDFEQAE
IYYQKALVKY QENGDRPNHI VNLIRLAELN FVQGRFDAAY TQMRDAQAQA EVMDNLHYNS
NIKEIEAKLL FAKGQYKQAQ QALREVYTMR EQVTDDKASP AISLIELLVT AAQGDHVKSA
LLYERYERQQ QEMLSNKIAS SLNDFQAKYN ATELQQQVDS LKQQQQLDKL EAQQRRQMTF
LAAGILILAF ISIVLLFRRS AERKATAMLE DKVKQRTKEL EELADQLSAA NEIKSQFLAN
ISHEIRTPLT SIMGQAQAII EGDVPAEQVA KELRVIYNNS QHLGELINDV LDLSKIEANK
LELVISTVSI CSLLADINAM FQPSASQKGI LFRINNKLPA SFGAEFDYIR VKQVLVNLCS
NAVKFTEQGE VELAITADEQ GVCFRVKDTG IGIAEDKLDA IFANFSQGDN SISRRFGGTG
LGLSLSQQLA QIMGGDISVS SVLGQGSTFS FYIPCRCMEM DERSNDTIQA ARALSFSGEV
VLAEDHEDNR RLIERLLTNL GIKVHSAANG EQAVELTLQH CPDLVLMDIQ MPKMDGLEAL
NLLRQCGYTQ PIIALTANAM THDIERYKAA GFTNHLAKPI EKEEFCRTLE HFLNVEIDAR
AAQSVDMSDL HESFMHTLPR EIESLVNAHA RNDLDEIKAV AHRLAGAAQM FASQTIAELV
CDIELAAKYQ DKEQVGVLIE DLANLELE
//
