ID   A0A0F4YJH7_TALEM        Unreviewed;       500 AA.
AC   A0A0F4YJH7;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Amine oxidase {ECO:0000256|RuleBase:RU000672};
DE            EC=1.4.3.- {ECO:0000256|RuleBase:RU000672};
GN   ORFNames=T310_8323 {ECO:0000313|EMBL:KKA17738.1};
OS   Rasamsonia emersonii CBS 393.64.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Rasamsonia.
OX   NCBI_TaxID=1408163 {ECO:0000313|EMBL:KKA17738.1, ECO:0000313|Proteomes:UP000053958};
RN   [1] {ECO:0000313|EMBL:KKA17738.1, ECO:0000313|Proteomes:UP000053958}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 393.64 {ECO:0000313|EMBL:KKA17738.1,
RC   ECO:0000313|Proteomes:UP000053958};
RA   Heijne W.H., Fedorova N.D., Nierman W.C., Vollebregt A.W., Zhao Z., Wu L.,
RA   Kumar M., Stam H., van den Berg M.A., Pel H.J.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Cu cation; Xref=ChEBI:CHEBI:23378;
CC         Evidence={ECO:0000256|RuleBase:RU000672};
CC       Note=Contains 1 topaquinone per subunit.
CC       {ECO:0000256|RuleBase:RU000672};
CC   -!- PTM: Topaquinone (TPQ) is generated by copper-dependent autoxidation of
CC       a specific tyrosyl residue. {ECO:0000256|PIRSR:PIRSR600269-51,
CC       ECO:0000256|RuleBase:RU000672}.
CC   -!- SIMILARITY: Belongs to the copper/topaquinone oxidase family.
CC       {ECO:0000256|ARBA:ARBA00007983, ECO:0000256|RuleBase:RU000672}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKA17738.1}.
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DR   EMBL; LASV01000568; KKA17738.1; -; Genomic_DNA.
DR   RefSeq; XP_013324350.1; XM_013468896.1.
DR   AlphaFoldDB; A0A0F4YJH7; -.
DR   STRING; 1408163.A0A0F4YJH7; -.
DR   GeneID; 25320583; -.
DR   OrthoDB; 34972at2759; -.
DR   Proteomes; UP000053958; Unassembled WGS sequence.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0008131; F:primary amine oxidase activity; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   GO; GO:0009308; P:amine metabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.10.450.40; -; 1.
DR   Gene3D; 2.70.98.20; Copper amine oxidase, catalytic domain; 2.
DR   InterPro; IPR000269; Cu_amine_oxidase.
DR   InterPro; IPR015798; Cu_amine_oxidase_C.
DR   InterPro; IPR036460; Cu_amine_oxidase_C_sf.
DR   InterPro; IPR016182; Cu_amine_oxidase_N-reg.
DR   PANTHER; PTHR10638:SF33; AMINE OXIDASE; 1.
DR   PANTHER; PTHR10638; COPPER AMINE OXIDASE; 1.
DR   Pfam; PF01179; Cu_amine_oxid; 2.
DR   SUPFAM; SSF49998; Amine oxidase catalytic domain; 1.
DR   SUPFAM; SSF54416; Amine oxidase N-terminal region; 1.
DR   PROSITE; PS01164; COPPER_AMINE_OXID_1; 1.
PE   3: Inferred from homology;
KW   Copper {ECO:0000256|ARBA:ARBA00023008, ECO:0000256|RuleBase:RU000672};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU000672};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU000672};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053958};
KW   TPQ {ECO:0000256|ARBA:ARBA00022772, ECO:0000256|PIRSR:PIRSR600269-51}.
FT   DOMAIN          115..185
FT                   /note="Copper amine oxidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01179"
FT   DOMAIN          195..468
FT                   /note="Copper amine oxidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01179"
FT   MOD_RES         238
FT                   /note="2',4',5'-topaquinone"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600269-51"
SQ   SEQUENCE   500 AA;  56214 MW;  8FECFEFC6C311FB2 CRC64;
     MLKLPENATV CIESWTYGTD GMNDMAERII MCYFYMRLSD HGDSNHYAYP LDICVEMSGD
     LTVKRILSLP LGENDRCGLL SEVGVKPFDR NKIHATSEYH PDLVNERRKT TKPYHVVQPQ
     GPSFHTQGNL LTWEKWKMRV GFNYVSATMS PVLFLVLIVQ REGLTLHDIT YDGRSVFYRL
     SLSEINGAGI NANNLKLVCC HEIDDGILWK HTNYRTGNAV VTRSRILVLQ TIITVGNYEY
     IFAFQFTQDA SINYEVRATG ILSTAPINLG DSVSYGTIVG PGVMAPYHQH LFSLRIDPAI
     DGHRNSLIVE ESHPMPIDDP NVHNPFGVDR LPGRVLKIVN ENVRNPITGG PVGYKLVPHY
     SQLVLAHPSS YHFKRSEFGE HAIWITRYHD DELYSSGKHT MQSLGGEGIA SWIRSRPAPV
     SVRNEDIVIW HTFGTTHNPR IEDWPVMPVE KMLVSLKPIN FFTRNPAIDV PISTQEENKS
     VLVEDDKGAA NVGGASCAKL
//