ID   A0A0F4Z554_TALEM        Unreviewed;       950 AA.
AC   A0A0F4Z554;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=Anaphase-promoting complex subunit 2 {ECO:0000256|ARBA:ARBA00016068};
GN   ORFNames=T310_0758 {ECO:0000313|EMBL:KKA25211.1};
OS   Rasamsonia emersonii CBS 393.64.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Rasamsonia.
OX   NCBI_TaxID=1408163 {ECO:0000313|EMBL:KKA25211.1, ECO:0000313|Proteomes:UP000053958};
RN   [1] {ECO:0000313|EMBL:KKA25211.1, ECO:0000313|Proteomes:UP000053958}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 393.64 {ECO:0000313|EMBL:KKA25211.1,
RC   ECO:0000313|Proteomes:UP000053958};
RA   Heijne W.H., Fedorova N.D., Nierman W.C., Vollebregt A.W., Zhao Z., Wu L.,
RA   Kumar M., Stam H., van den Berg M.A., Pel H.J.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00330, ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKA25211.1}.
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DR   EMBL; LASV01000032; KKA25211.1; -; Genomic_DNA.
DR   RefSeq; XP_013331823.1; XM_013476369.1.
DR   AlphaFoldDB; A0A0F4Z554; -.
DR   STRING; 1408163.A0A0F4Z554; -.
DR   GeneID; 25312812; -.
DR   OrthoDB; 2786196at2759; -.
DR   Proteomes; UP000053958; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR044554; APC2-like.
DR   InterPro; IPR014786; APC2_C.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR45957; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR   PANTHER; PTHR45957:SF1; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR   Pfam; PF08672; ANAPC2; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   SMART; SM01013; APC2; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053958};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          593..814
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          25..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          93..114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..60
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        97..114
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   950 AA;  104900 MW;  B7BBD20D8A9B6227 CRC64;
     MSQNAPLSMS RKRVFDSVFA PTSLKSLAPT TGATPASAFT PDQPLGTTTQ PSTAANESDV
     KIEESSPEQI IWDRAWHAAT TFLSFPDRGF EVLTTGDPDG AQSTTSRLDS SSLPSREISD
     SLAYLLAPSS RGRALRAGLK EHDLVEWYGN EMRRHFLTNF RAGFVQLLEG PAQDGLLSKI
     VGYLQSAQRI YYTPFLRFVV PHLDAADQEA AFLRLRRSFH AIVAYSLPSS RTSALLATEL
     TNGAVVILGI ESAKEERAVY SEAGDQNDGG MDDMDIDRKY STSYRVWKDE PSEAARIQMM
     TEGEDAQISA ARERLLRLLG RVQDVGLGGE RGQKAFARVM NNMMTEFITA TYTGQWEAPS
     LVTQHLRLWT ENVFARLVVE VLNIFRPYDV EGRTEGQLDV TLGDVGKWQE IAIARLGALR
     TSELFDVIVE WDSSSGAIED LRQYANNPAT RFSLASSFIG MLNQRLLHPG ASTVEILQLY
     ISIIRAFNLL DPKGVLLDRI ARPIRKYLRD REDTVKVIVS GLLADAPDTE GQNTASSSDT
     LVELSAELSK AHQQSLQVDS GELDWDDMNW MPDPIDAAAD YKKSKGSDVI GSLISLFESK
     EAFVKELQNL LSERLLKKRA DFDQEMSVLE LLKVRFGDGA LQACEVMLRD VLDSKRVDAV
     VRSDQGLIGK QPSQEAMTPD RSMAAAEQAE EMPQLHAKIL SRFFWPTLQD QNFKVPDEIA
     SLQQRYAAGF ESLKQSRKLT WLNALGQVTV ELDLEDRVFT DEVTTWQATV IYAFQSPGGH
     TGSSTSPVTK TVAELSDQLE MPASLVRSAC LFWVSKRILV EVQRDTFRVL EVLPNEEERD
     AAGGADSDMA GNSSTEASAA AAADAAAAAE RESANAAAME KMNLYWQFIV GMLTNQGAMP
     LQRIVMMLKI AVPGGFPYSN EDLREFLAGM VAQGKLEIVS GGNYKLIPQR
//