ID A0A0F4Z925_9PEZI Unreviewed; 1042 AA.
AC A0A0F4Z925;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TD95_004862 {ECO:0000313|EMBL:KKA26845.1};
OS Thielaviopsis punctulata.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Ceratocystidaceae; Thielaviopsis.
OX NCBI_TaxID=72032 {ECO:0000313|EMBL:KKA26845.1, ECO:0000313|Proteomes:UP000033483};
RN [1] {ECO:0000313|EMBL:KKA26845.1, ECO:0000313|Proteomes:UP000033483}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR-DP1 {ECO:0000313|EMBL:KKA26845.1};
RA Radwan O., Al-Naeli F.A., Rendon G.A., Fields C.;
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKA26845.1}.
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DR EMBL; LAEV01001970; KKA26845.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F4Z925; -.
DR OrthoDB; 1330110at2759; -.
DR Proteomes; UP000033483; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF154; DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11660)-RELATED; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000033483};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 48..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 493..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 610..635
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 668..687
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 693..712
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 47..195
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 219..388
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 400..682
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 995..1042
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1042 AA; 115755 MW; 2BE52AD80C784492 CRC64;
MSLPATAGAV LRRLFARDGD DNNSNDAGQE LLDLLKDPFS GDISSTSLWT AISVSFGFTA
FIAICFSLLR PYNQSVYAPK LKHADEKHAP PALGKEPWSW FIPLWRTSET DTVSHIGMDA
AIFIRFTKML RNIFLTLTVC VCPVIIPTNL TSGTDNAGRS WLSNIGPSTV YGKAHWADVI
AAWVTTLIVM AYLWWNYRRV LALRRAYFNT EEYQNSLHAR TLMLTDLPRD RCSDEGIARV
IDSVAPNSSF ARTAVARNVR DLPTLISEHE RIVRKLEKVL AIYLKDPHQL PPARPLCRVS
RKDPSHGTYP RGQKVDAIEY LTQRIKSLEV QIREVRTTVD RRSTMPYGFA SYSDISEAHS
IAYTIKGKKP SGTTIVLAPR PEDIIWSNMP LSPSVRSWKT IMVNLWVTLL TVLWVVPNAM
IAIFLVNLSN LGRVWTPFND ELKEHPTFWG MFQGVANPAL TSLVYLALPI IFRRLSIMAG
DRTKTGRDRH VTAKLYAFFV FNNLIVFSVF STIWAVVAGV VADTSKGMDA WRAIIKNNPF
GALLESLCGN SPFWVNWLLQ RQLGAAIDLA QLWPLVYRSV MRKFWHPTPR ELIELTAPPP
FEYASYYNYF LFYATVTLFY AGIQPLVLPA AAIYFSIDVW LKKYLLLYVF ITKNESGGII
WRVLYNRMLF ATLLSQLIFL LIIWARGTDS RNMQAYCLAP LPVLLILFKI YCAKAFDTKM
YYYACTNMDK EAPIADPTKD GRLRSEKLAS RFGHPSLYKP LVTPMVHAKA QDMLHIVYSG
RLTNGRDGSG VNDFTSVSGY SDTFAMDSMK SSGAPGKTMG VPGFELVPES QMDFEYYKNR
PEFASEHGAG ALFGSPSDII RTDTPSTTFG DNSRPGTPAQ VYGGMTGGTV PTIPQVGSNT
GYAPYRSHTP ASIASGNGGY ATPPPPNAFL GQADMATSSV AAMRTRSPLY EQANDSSSRL
VSSAADMAMA PPAWQTQGYD AQSGMREPTL PAVHVPGPST GALGGGPQGY SGLAQAEVPE
TDPAQYDYFR GSQRRRPGDG YY
//
