ID   A0A0F4Z987_9PEZI        Unreviewed;      1258 AA.
AC   A0A0F4Z987;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   ORFNames=TD95_001628 {ECO:0000313|EMBL:KKA26661.1};
OS   Thielaviopsis punctulata.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Microascales; Ceratocystidaceae; Thielaviopsis.
OX   NCBI_TaxID=72032 {ECO:0000313|EMBL:KKA26661.1, ECO:0000313|Proteomes:UP000033483};
RN   [1] {ECO:0000313|EMBL:KKA26661.1, ECO:0000313|Proteomes:UP000033483}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CR-DP1 {ECO:0000313|EMBL:KKA26661.1};
RA   Radwan O., Al-Naeli F.A., Rendon G.A., Fields C.;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKA26661.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LAEV01002045; KKA26661.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F4Z987; -.
DR   OrthoDB; 5477883at2759; -.
DR   Proteomes; UP000033483; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF17; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   Pfam; PF05183; RdRP; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033483};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
SQ   SEQUENCE   1258 AA;  143507 MW;  E762C9281E3C8F38 CRC64;
     MDVYLRNVPL HCSKKILHDG LATYLHELNI TDWACDKMVQ QRCGRILFAH LEDAEKFLRA
     YTAQSPKKSK LLILGTGILA EKGKLKVSKT DIAHVKHVAK QRKIYVSEMR ANKVQPQHPI
     VRPLLEVCCG KNQAIAGTNI IGFVAEASTT QSAEVKFSRM AMFINFSNKA QIEILYDSIW
     EATTGDKNEI LFILQYPPRF FVSISLEDQV AASMASGTRR GPSYTKTRVS YLNNLPNHML
     ISGTCLVYKI RIDGTYQAFQ SLDRELSSRR LFPLYSYHPF STLQPTRTLS YRYNHAEFKR
     WISQETVHNL DFSTCFQLQL AVWNNFLPPN IALQLGQLIS EKTHKMPHDK TPLFSSEAMK
     RVITDIPYPS LTTEVNVLSP QSIFSRLQKA EKDLRIRSSM GNLMENNKAQ EKLVLVHKAW
     VTPARITLIG PEYESKNRVL RKFHNYLDYF LRVQFCDEDG DDVRFSGRIS NEQLMQRFLD
     IFEHGIQIGG RVFSFLGFSH SSLRSHSAWF TAPFFHRESN TLQTHIDIIR NLGNFSDIRT
     PARCAARIGQ AFSETPFSVS LGENDIKYCY IPDLKSPDGK RVFSDGVGSI SYDAVEVIWN
     NIPNNESFPT CFQVRWGGAK GMLALDARLS GKVICVRKES MVKFESTDIH ELEICDMASR
     PLRLVLNRQI IKILEDMGVP NEWFIDIQAG EIEALRTVTS DPYNTSSFLQ DQLIGRRIQL
     SSFIRKLHNL GINYLQDIFM RRVVEMAVLR ELRLLKNKAR IPIRKGVTLF GIVDETGFLE
     PHEVYVAIDK PYLDMFDDYP AAGRLLVTRS PALHPGDIQG AVQKTPPEGH PLRELTNCIV
     FSQRGNRDLP SQLSGGDLDG DIYNVIWDPA VVNNNDIKLF EPADYPRVTP KTLDRKVERE
     DIAKFFVDFM RTDQLGVIAN RHQILADQKP AGTLDFECLK LAEMHSNAVD FSKTGLAVDV
     NEMPRAPRYR PDFMAPSPPA HVYKHGEIKI QQDIVNPDAD PFGEEDEIAP AHRYYESERI
     LGILYRNVDE RNIWDATKMV NVKSDDTTVW SQIQAYVDGV IRSTVGQREI DWMSKKREAA
     ELRSHYQFSM QDIMQECAPN YMNPLSEVEV FCGFIFSREG SQSRRQREAS IKIGGRVDEL
     TAFIAQRMRC RDRPPTDIKR KYEALEMCLA CFKLQNSSIR PSAEERLFGG AQERGDEVLK
     GFRVIAGSCL LRELAAVVLA LQRAHKEEVM AAEANKYLAP GVASYMDSIA ERFDKMRV
//