ID A0A0F5ERT0_AVIPA Unreviewed; 109 AA.
AC A0A0F5ERT0;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Multidrug efflux SMR transporter {ECO:0000313|EMBL:RZN58742.1};
DE SubName: Full=Quaternary ammonium determinant C {ECO:0000313|EMBL:SUU97832.1};
GN Name=qacC {ECO:0000313|EMBL:SUU97832.1};
GN ORFNames=EIG79_07225 {ECO:0000313|EMBL:RZN58742.1}, HBL79_02560
GN {ECO:0000313|EMBL:QIR11218.1}, NCTC10926_01230
GN {ECO:0000313|EMBL:SUU97832.1}, OY678_07180
GN {ECO:0000313|EMBL:WAL55794.1};
OS Avibacterium paragallinarum (Haemophilus gallinarum).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Avibacterium.
OX NCBI_TaxID=728 {ECO:0000313|EMBL:RZN58742.1, ECO:0000313|Proteomes:UP000294229};
RN [1] {ECO:0000313|EMBL:SUU97832.1, ECO:0000313|Proteomes:UP000254620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10926 {ECO:0000313|EMBL:SUU97832.1,
RC ECO:0000313|Proteomes:UP000254620};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:RZN58742.1, ECO:0000313|Proteomes:UP000294229}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA-3 {ECO:0000313|EMBL:RZN58742.1,
RC ECO:0000313|Proteomes:UP000294229};
RA Hellmuth J.E., Boucher C.E., Cason E.D.;
RT "Sequencing Av. paragallinarum serogroups.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QIR11218.1, ECO:0000313|Proteomes:UP000503595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ESV-135 {ECO:0000313|EMBL:QIR11218.1,
RC ECO:0000313|Proteomes:UP000503595};
RA Cobos-Justo M.E., Sanchez-Alonso M.P., Negrete-Abascal E., Perez V.,
RA Soriano-Vargas E., Castelan H., Vazquez-Cruz C.;
RT "Comparison of the genome sequence of three Mexican strains of Avibacterium
RT paragallinarum.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:WAL55794.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C-AP1 {ECO:0000313|EMBL:WAL55794.1};
RA Zhang J.P.;
RT "The genome of Avibacterium paragallinarum.";
RL Submitted (NOV-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU003942};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU003942}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
CC {ECO:0000256|ARBA:ARBA00038032, ECO:0000256|RuleBase:RU003942}.
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DR EMBL; CP050316; QIR11218.1; -; Genomic_DNA.
DR EMBL; RQXS01000030; RZN58742.1; -; Genomic_DNA.
DR EMBL; UFSW01000001; SUU97832.1; -; Genomic_DNA.
DR EMBL; CP113786; WAL55794.1; -; Genomic_DNA.
DR RefSeq; WP_046097420.1; NZ_VXDA01000024.1.
DR STRING; 728.VY92_08695; -.
DR GeneID; 66255467; -.
DR eggNOG; COG2076; Bacteria.
DR OrthoDB; 9808638at2; -.
DR Proteomes; UP000254620; Unassembled WGS sequence.
DR Proteomes; UP000294229; Unassembled WGS sequence.
DR Proteomes; UP000503595; Chromosome.
DR Proteomes; UP001163112; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 1.10.3730.20; -; 1.
DR InterPro; IPR000390; Small_drug/metabolite_transptr.
DR InterPro; IPR045324; Small_multidrug_res.
DR PANTHER; PTHR30561:SF1; MULTIDRUG TRANSPORTER EMRE; 1.
DR PANTHER; PTHR30561; SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE; 1.
DR Pfam; PF00893; Multi_Drug_Res; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|RuleBase:RU003942, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 26..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 109 AA; 11409 MW; ED069A1045DC51D1 CRC64;
MAWLWLALAI VSEVFGSTML KLSEGFSKLL PSAGVVLGFG LAFYFLSLAL KTLPLGTAYA
VWAGVGLVLT AIVSMLFFGT KADAMGLLGI AFILVGVVIL NAFSHMAAH
//
