ID A0A0F5EYE6_AVIPA Unreviewed; 562 AA.
AC A0A0F5EYE6;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Long-chain-fatty-acid--CoA ligase {ECO:0000256|ARBA:ARBA00039545};
DE EC=6.2.1.3 {ECO:0000256|ARBA:ARBA00026121};
DE AltName: Full=Long-chain acyl-CoA synthetase {ECO:0000256|ARBA:ARBA00042773};
GN Name=fadD {ECO:0000313|EMBL:SUU97040.1};
GN ORFNames=NCTC10926_00404 {ECO:0000313|EMBL:SUU97040.1};
OS Avibacterium paragallinarum (Haemophilus gallinarum).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Avibacterium.
OX NCBI_TaxID=728 {ECO:0000313|EMBL:SUU97040.1, ECO:0000313|Proteomes:UP000254620};
RN [1] {ECO:0000313|EMBL:SUU97040.1, ECO:0000313|Proteomes:UP000254620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10926 {ECO:0000313|EMBL:SUU97040.1,
RC ECO:0000313|Proteomes:UP000254620};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UFSW01000001; SUU97040.1; -; Genomic_DNA.
DR RefSeq; WP_046098223.1; NZ_VXDA01000010.1.
DR AlphaFoldDB; A0A0F5EYE6; -.
DR STRING; 728.VY92_07900; -.
DR eggNOG; COG0318; Bacteria.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000254620; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:UniProtKB-EC.
DR CDD; cd05936; FC-FACS_FadD_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF8; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:SUU97040.1}.
FT DOMAIN 29..421
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 471..545
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 562 AA; 63311 MW; 652B46A372727B7D CRC64;
MEKPWFINYP EGAEKHIDTS AYENILDMFD KAVREHPDRP AYINMGQVLT FRKLEERSRA
FAAYLQNELK LQQGDPVALM MPNLLQYPIA LFGILRAGMV VVNVNPLYTP RELEHQLQDS
GAKAIVVVSN FASTLEKVVF NTDVKHVILT RMGDQLSFGK RTLVNFVVKY IKKLVPKYKL
PHAVTFREVL AVGKFRQYVR PQISANDLAF LQYTGGTTGV AKGAMLSHHN IITNVFQAKW
IAYPFVGDHS KERKAILALP LYHVFALTVN CLLFIELGVT AILITNPRDI DGFVKEMKKH
RFVAITGVNT LFNALLNNEN FKEVDFSSLK LSVGGGMAIQ QSVATRWHET TGCNIIEGYG
MTECSPLIAA CPINVVKHNG TIGVPVPNTD IKILKENGEE AQLGEAGELW VKGDQVMQGY
WQRPEATAEV LKDGWLATGD IVIMDESYSL RIVDRKKDMI IVSGFNVYPN EIEDVIMLNY
KVAEVVAIGV PNEISGETIK VFVVKKDESL TRDELRQHCR QHLTGYKVPK EIEFRDELPK
SNVGKILRRV LREEELAKRP AN
//
