ID A0A0F5EZF4_AVIPA Unreviewed; 211 AA.
AC A0A0F5EZF4;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=2-dehydro-3-deoxy-phosphogluconate aldolase {ECO:0000256|ARBA:ARBA00013063};
DE EC=4.1.2.14 {ECO:0000256|ARBA:ARBA00013063};
GN Name=eda {ECO:0000313|EMBL:RZN58548.1};
GN ORFNames=EIG79_07395 {ECO:0000313|EMBL:RZN58548.1}, NCTC10926_00605
GN {ECO:0000313|EMBL:SUU97234.1};
OS Avibacterium paragallinarum (Haemophilus gallinarum).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Avibacterium.
OX NCBI_TaxID=728 {ECO:0000313|EMBL:RZN58548.1, ECO:0000313|Proteomes:UP000294229};
RN [1] {ECO:0000313|EMBL:SUU97234.1, ECO:0000313|Proteomes:UP000254620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10926 {ECO:0000313|EMBL:SUU97234.1,
RC ECO:0000313|Proteomes:UP000254620};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:RZN58548.1, ECO:0000313|Proteomes:UP000294229}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA-3 {ECO:0000313|EMBL:RZN58548.1,
RC ECO:0000313|Proteomes:UP000294229};
RA Hellmuth J.E., Boucher C.E., Cason E.D.;
RT "Sequencing Av. paragallinarum serogroups.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-
CC phosphate + pyruvate; Xref=Rhea:RHEA:17089, ChEBI:CHEBI:15361,
CC ChEBI:CHEBI:57569, ChEBI:CHEBI:59776; EC=4.1.2.14;
CC Evidence={ECO:0000256|ARBA:ARBA00000654};
CC -!- SIMILARITY: Belongs to the KHG/KDPG aldolase family.
CC {ECO:0000256|ARBA:ARBA00006906}.
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DR EMBL; RQXS01000032; RZN58548.1; -; Genomic_DNA.
DR EMBL; UFSW01000001; SUU97234.1; -; Genomic_DNA.
DR RefSeq; WP_046097961.1; NZ_VXDA01000014.1.
DR AlphaFoldDB; A0A0F5EZF4; -.
DR STRING; 728.VY92_09395; -.
DR eggNOG; COG0800; Bacteria.
DR OrthoDB; 9805177at2; -.
DR Proteomes; UP000254620; Unassembled WGS sequence.
DR Proteomes; UP000294229; Unassembled WGS sequence.
DR GO; GO:0008675; F:2-dehydro-3-deoxy-phosphogluconate aldolase activity; IEA:UniProtKB-EC.
DR CDD; cd00452; KDPG_aldolase; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR000887; Aldlse_KDPG_KHG.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR031337; KDPG/KHG_AS_1.
DR InterPro; IPR031338; KDPG/KHG_AS_2.
DR NCBIfam; TIGR01182; eda; 1.
DR PANTHER; PTHR30246; 2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE; 1.
DR PANTHER; PTHR30246:SF2; KHG_KDPG ALDOLASE; 1.
DR Pfam; PF01081; Aldolase; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS00159; ALDOLASE_KDPG_KHG_1; 1.
DR PROSITE; PS00160; ALDOLASE_KDPG_KHG_2; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:RZN58548.1}.
SQ SEQUENCE 211 AA; 22574 MW; 9B789DFEF4AD655D CRC64;
MNTAQIIEKL REFKVIPVIA LDNAQDILPL AETLAKNGLP VVEITFRSAA AEEAIRLIRQ
HNPNILIAAG TVLTSEQVVQ AKNAGADCIV TPGFNPKTVK LCQELNIPVM PGVNNPMSIE
AALELGITAV KFFPAEASGG VKMIKALLGP YAQLQIMPTG GISVNNIKDY LAIPNVVACG
GSWFVEKSLI NSHNWEEIGR LVREAVAITN A
//
