ID A0A0F5N095_9MYCO Unreviewed; 581 AA.
AC A0A0F5N095;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
DE Flags: Fragment;
GN ORFNames=WR43_04785 {ECO:0000313|EMBL:KKC00441.1};
OS Mycolicibacter arupensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacter.
OX NCBI_TaxID=342002 {ECO:0000313|EMBL:KKC00441.1, ECO:0000313|Proteomes:UP000034416};
RN [1] {ECO:0000313|Proteomes:UP000034416}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GUC1 {ECO:0000313|Proteomes:UP000034416};
RA Greninger A.L., Cunningham G., Chiu C.Y., Miller S.;
RT "Genome sequence of Mycobacterium arupense GUC1.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKC00441.1}.
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DR EMBL; LASW01000012; KKC00441.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F5N095; -.
DR STRING; 342002.BST15_00500; -.
DR PATRIC; fig|342002.3.peg.1304; -.
DR Proteomes; UP000034416; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR PANTHER; PTHR11070:SF55; DNA HELICASE; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KKC00441.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 147..264
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13361"
FT DOMAIN 410..559
FT /note="PD-(D/E)XK endonuclease-like"
FT /evidence="ECO:0000259|Pfam:PF12705"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KKC00441.1"
SQ SEQUENCE 581 AA; 61451 MW; B895D4019AB2DD62 CRC64;
ELARPHASSA PASAAEIAAA AGPDADTACL ADALADPGPA ERYSAVGHRR IVALAEELTL
LRGHLWHPLP DLVAEVRRVL GLDCEVLAAQ PLTTGGSGTD QLDAFADVVA GYADAAGAPA
SLPGLLAYLE AAEVVENGLA PAAPAVAADR VQILTVHAAK GLEWQVVAIP HLVARVFPST
ASRRSWLSDA AELPPLLRGD RAQRGGEFVE GVPILDTDAV THRKQLSDAI AEHQRRLDQR
RVDEERRLLY VAVTRAEDTL LVSGHHWGAG ETKPRGPSVF LTEIKAVIDN AADAGTPCGV
VQHWAQEPAE GEANPLRDSA EEGVWPVDPL AGRRGHVDHG AALVSAQLQA DESSDGELPS
SPWAADVDAL LAERASSAGQ PVRTLPQQLS VSGLVELSRD PDGAPQRLSR RLPARPDPHA
LLGTAFHDWV QRLYGAEHLF ELDDLPGAAD ADMARADAQE LAHLQAAFLE SPWAARTPTA
VEVPFEMTLG THVVRGRIDA VFAEPDGGVT VVDWKTGTAP DGPDARRHAA VQLAVYRLAW
AALSGCPVSQ VRAAFHYVRA GSTVVPDELP EHHELAALLD S
//
