ID A0A0F5VBV9_9GAMM Unreviewed; 454 AA.
AC A0A0F5VBV9;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Sodium:proton antiporter {ECO:0000313|EMBL:KKC98989.1};
GN ORFNames=KY46_15435 {ECO:0000313|EMBL:KKC98989.1};
OS Photobacterium halotolerans.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=265726 {ECO:0000313|EMBL:KKC98989.1, ECO:0000313|Proteomes:UP000033633};
RN [1] {ECO:0000313|EMBL:KKC98989.1, ECO:0000313|Proteomes:UP000033633}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MELD1 {ECO:0000313|EMBL:KKC98989.1,
RC ECO:0000313|Proteomes:UP000033633};
RA Mathew D.C., Huang C.-C.;
RT "Mercury Reductase activity and rhizosphere competence traits in the genome
RT of root associated Photobacterium halotolerans MELD1.";
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NhaC Na(+)/H(+) (TC 2.A.35) antiporter
CC family. {ECO:0000256|ARBA:ARBA00038435}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKC98989.1}.
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DR EMBL; JWYV01000014; KKC98989.1; -; Genomic_DNA.
DR RefSeq; WP_046221531.1; NZ_JWYV01000014.1.
DR AlphaFoldDB; A0A0F5VBV9; -.
DR STRING; 265726.KY46_15435; -.
DR PATRIC; fig|265726.11.peg.1352; -.
DR OrthoDB; 9790605at2; -.
DR Proteomes; UP000033633; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR PANTHER; PTHR33451; MALATE-2H(+)/NA(+)-LACTATE ANTIPORTER; 1.
DR PANTHER; PTHR33451:SF4; NA+_H+ ANTIPORTER-RELATED; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 3: Inferred from homology;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000033633};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..225
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 454 AA; 46926 MW; 5C542A42CDC2DE9E CRC64;
MLHANPHTHS DSPSPSALAL LPLAVFLSLF IGVGSYLTWQ GVDFAFYQLP APVAALPAIL
VAIVLSKDAL NKTIEDFMRG VGHSDIIAMC MIYLLAGAFA AVAKATGGVD ATVNLGLSLL
PPSLILPGIF VIAAFIATAM GTSMGTIAAV APVALGIADT ADLDIALTAG VVLSGAMFGD
NLSIISDTTI AATRSQGCAM RDKFRENIAI ALPAALAAIL LFLFHSTPSD APTVTSIEWL
KVLPYVTILV LAVSGVNVFV VLSLGIILAG GVGLSSVSDY SLASWSKDIY AGFGNMQEIF
LLSLLIGGMS ELMRRQGGLA FLTLLVSKLI SGFGKKTDGE QSQKASEMGI AGLVSLTNVC
TANNTVAIIV AGGVARELAE QNAVTPRRSA SLLDIFSCVI QGVLPYGAQA LLLGSVFGLS
PLAVVSHSYY CFFLAASALI AILIKHQQIR TAAA
//
