ID A0A0F5VKM5_9ACTN Unreviewed; 410 AA.
AC A0A0F5VKM5;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Aldehyde dismutase {ECO:0000313|EMBL:KKD02731.1};
GN ORFNames=TN53_38860 {ECO:0000313|EMBL:KKD02731.1};
OS Streptomyces sp. WM6386.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415558 {ECO:0000313|EMBL:KKD02731.1, ECO:0000313|Proteomes:UP000033641};
RN [1] {ECO:0000313|EMBL:KKD02731.1, ECO:0000313|Proteomes:UP000033641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6386 {ECO:0000313|EMBL:KKD02731.1,
RC ECO:0000313|Proteomes:UP000033641};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKD02731.1}.
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DR EMBL; JXTE01000115; KKD02731.1; -; Genomic_DNA.
DR RefSeq; WP_046263560.1; NZ_JXTE01000115.1.
DR AlphaFoldDB; A0A0F5VKM5; -.
DR PATRIC; fig|1415558.3.peg.845; -.
DR OrthoDB; 241504at2; -.
DR Proteomes; UP000033641; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08282; PFDH_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR014184; HCHO_DH_non_GSH.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR02819; fdhA_non_GSH; 1.
DR PANTHER; PTHR42813:SF3; GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000033641};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 46..155
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 208..274
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 410 AA; 42711 MW; F28F028C41E223A0 CRC64;
MSATGNRAVA YLKPGAVEVR TIDYPTLELQ DGPGVAAANV GRKCRHGVIL KVLASNICGS
DQHMVRGRTT APEGLVLGHE ITGEVVERGP DVETLDVGDI VSVPFNIACG RCRNCKERKT
GICLNVNPAR PGAAYGYVDM GGWVGGQAEY AMVPYADFNL LKFPDRDQAR EKLLDLTMLS
DIFPTGFHGV VSSGAGVGST VYVAGAGPVG LAAAASAQLL GAAVVIVGDL NAERLAQARS
FGCETVDVSR GSVGEQIAQI LGEPEVDAAV DAVGFEARAH GPQAPEAPAT VLNSLMGITR
AGGALGIPGL YVTDDPGGVD ADAKSGTLKV RLGLGWAKSH RFTTGQCPVM QYHRNLMRAI
LHGRVHIAKA VNATVIGIED APRGYAEFDQ GASRKYVLDP HGALDGVRPV
//
