ID A0A0F5VV28_9ACTN Unreviewed; 351 AA.
AC A0A0F5VV28;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KKD06029.1};
GN ORFNames=TN53_21275 {ECO:0000313|EMBL:KKD06029.1};
OS Streptomyces sp. WM6386.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415558 {ECO:0000313|EMBL:KKD06029.1, ECO:0000313|Proteomes:UP000033641};
RN [1] {ECO:0000313|EMBL:KKD06029.1, ECO:0000313|Proteomes:UP000033641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6386 {ECO:0000313|EMBL:KKD06029.1,
RC ECO:0000313|Proteomes:UP000033641};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKD06029.1}.
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DR EMBL; JXTE01000033; KKD06029.1; -; Genomic_DNA.
DR RefSeq; WP_046260163.1; NZ_JXTE01000033.1.
DR AlphaFoldDB; A0A0F5VV28; -.
DR PATRIC; fig|1415558.3.peg.4286; -.
DR OrthoDB; 3226810at2; -.
DR Proteomes; UP000033641; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000033641};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 11..65
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 351 AA; 37491 MW; 46672E8544A827D4 CRC64;
MTRKSEDASR STIRDVAARA GVSASTVSRV LGGVYPVSAA TRTRVMRAVR EMDYVADARA
KAIAGVGTPT LAFVLEDITG PSFALMAHGV EREATRLGHL CLVCSTEGDA RHEVEFVEMM
RAQRAAAVIL VGGGADTAEY RERTRRMADS LASAGSRLVL CGRPPLGPGA PVTVIEYDNE
GGAYALVAHV LVQGHQRVLF LGGKSDHTTA QGRERGYLAA HRARGVEPAE ELVLHGDFTR
DSGHRLMREA LEQKLDFTAV VAATDMVAAG ALTALHEAGL SVPRDVSLAG YDDIPFARDL
HPALTTVHVP YEELGRLAVR TALGREPNTP DEHLLLGTHV VVRDSVAPLK E
//
