ID A0A0F5VWZ9_9ACTN Unreviewed; 353 AA.
AC A0A0F5VWZ9;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KKD06714.1};
GN ORFNames=TN53_17325 {ECO:0000313|EMBL:KKD06714.1};
OS Streptomyces sp. WM6386.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415558 {ECO:0000313|EMBL:KKD06714.1, ECO:0000313|Proteomes:UP000033641};
RN [1] {ECO:0000313|EMBL:KKD06714.1, ECO:0000313|Proteomes:UP000033641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6386 {ECO:0000313|EMBL:KKD06714.1,
RC ECO:0000313|Proteomes:UP000033641};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKD06714.1}.
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DR EMBL; JXTE01000024; KKD06714.1; -; Genomic_DNA.
DR RefSeq; WP_046259407.1; NZ_JXTE01000024.1.
DR AlphaFoldDB; A0A0F5VWZ9; -.
DR PATRIC; fig|1415558.3.peg.3139; -.
DR OrthoDB; 9785139at2; -.
DR Proteomes; UP000033641; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01574; PBP1_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000033641};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 22..76
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 353 AA; 37700 MW; 2445770BB4B926A4 CRC64;
MSSSAAPAPK GRSRRNFAGA RPVMDDVARL AGVSKQTVSR VLNDNPAVRP ETREAVQAAM
RSLGYRPSRS ARSLASGRTR MLGVISFDAA RYGPANILTA INTAAQEAGY LLSSIALDDT
ADHDTVTEAV DRLSAEGADG VIAIAPQHRV GRALADAGLD TPLVVMENEV RGSTPLATAD
SWAGARKAVE HLLRLGHDTV WHIAGPTGWT SADQRIGSWR ETLTAAGAEI PELLVGDWSS
DSGYETGRLL ARRPDVTAIF ASNDQMALGL LHALHEAGRR VPDDVSVVGY DDIPEAAHLL
PPLTTVRTDF AEIGTRALRL LLDRIDGRAE ERTEPVIPVE LIVRRSSGRP PRG
//
