ID   A0A0F5W3T0_9ACTN        Unreviewed;      1627 AA.
AC   A0A0F5W3T0;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:KKD09018.1};
GN   ORFNames=TN53_04385 {ECO:0000313|EMBL:KKD09018.1};
OS   Streptomyces sp. WM6386.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1415558 {ECO:0000313|EMBL:KKD09018.1, ECO:0000313|Proteomes:UP000033641};
RN   [1] {ECO:0000313|EMBL:KKD09018.1, ECO:0000313|Proteomes:UP000033641}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WM6386 {ECO:0000313|EMBL:KKD09018.1,
RC   ECO:0000313|Proteomes:UP000033641};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKD09018.1}.
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DR   EMBL; JXTE01000005; KKD09018.1; -; Genomic_DNA.
DR   RefSeq; WP_046257002.1; NZ_JXTE01000005.1.
DR   PATRIC; fig|1415558.3.peg.5947; -.
DR   OrthoDB; 9815222at2; -.
DR   Proteomes; UP000033641; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd17922; DEXHc_LHR-like; 1.
DR   CDD; cd18796; SF2_C_LHR; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013701; DEAD/DEAH_assoc.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47962:SF5; ATP-DEPENDENT HELICASE LHR-RELATED; 1.
DR   PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08494; DEAD_assoc; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:KKD09018.1};
KW   Hydrolase {ECO:0000313|EMBL:KKD09018.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033641}.
FT   DOMAIN          35..228
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          271..450
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          1458..1498
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1627 AA;  173418 MW;  F7A30DA8706C2F51 CRC64;
     MVSDARRALD GFSPATRGWF TGAFDAPTAA QAGAWNAIKE GSDVLVVAPT GSGKTLAAFL
     AALDQLTSTP PPADPRKRCR VLYVSPLKAL AVDVERNLRS PLTGIRQESV RLGLPEPEVK
     VGIRSGDTPA AERRALSTRP PDILITTPES LFLMLTSATR DALTGIETVI LDEVHAVAGT
     KRGAHLALSL ERLDELLPKP ARRIGLSATV RPVDEVARYL SPRRKVEIVQ PKSGKEFDLS
     VVVPVEDLGE LGGSPVADGT EGAERPSIWP HVEERIADLV QSHRSTIVFA NSRRLAERLC
     NRLNEIAYER ATGETLDEHH APAELMGGSG AAQGAPPVIA RAHHGSVSKE QRALVEEDLK
     AGRLPAVVAT SSLELGIDMG AVDLVVQVES PPSVASGLQR VGRAGHQVGA VSTGVVFPKY
     RGDLVQAAVV TERMRTGSIE SLKVPANPLD VLAQQLVAMT SMDTWQLDDL LAMVRRAAPF
     ASLPDSAFTA VLDMLAGRYP SDAFAELRPR VVWDRVAGTI TGRPGAQRLA VTSGGTIPDR
     GLFGVFLAGA DPKKGGGRVG ELDEEMVYES RVGDVFTLGT SSWRIEDITR DRVLVSPAPG
     VPGRLPFWKG DQLGRPLELG RAVGAFLREV GSLPKDKARP RLLAAGLDTW AADNVLAYLA
     EQREACGHIP DDRTIVVERF RDELGDWRVV VHSPFGAQVH APWALALGAK LSERYGMDAQ
     VMHADDGIVL RLPDADLMGL DLLDQEPTKL GTEYDADQAP VGAADVVFDK GEVDQVVTDQ
     VGGSALFASR FRECAARALL LPRRSPGKRT PLWQQRQRAA QLLQVASEFG SFPIVLEAVR
     ECLQDVFDVP GLVELMGDLE SRKVRLVEVT TPEPSPFARS LLFGYVAQFL YEGDSPLAER
     RAAALSLDSR LLAELLGQAE LRELLDAEVL AELEQELQWL TEDRRAKDAE SVADLLRLLG
     PLTDTELAER GAEPPWAQEL ARARRAIKVR IAGTDHWAAI EDAGRLRDAL GTALPVGVPE
     AFTEPVKDPL GDLLARHART HGPFTSASAA ARFGLGVAVT EGALQRLSAN GRVVQGEFHP
     AGIGQEWCDA AVLRRLRRRS LAALRHELEP VSPPALAQFL PQWQHIGKGH GLRGADGLVR
     AVEQLQGASV PASALEKLVL PSRVAHYTPA MLDELTSAGE LVWAGAGSLP GKDGWVSLYL
     ADAAPLLLPP PHPLELTALH ESVLTALSGG YGLFFRQIAD QVRATTHPDA TDPQLADTVW
     DLAWSGRLTN DTLTPMRSLL GSGRTAGSTA HRAKRTVPRG RYGSLTAAAR PASRTGPPTV
     AGRWSLLPDR EPDPTLRAHA LARTLLDRHG VVTRGAVSAE GVEGGFSATY RILSAFEETG
     QARRGYVVEG LGAAQFAMDG AVDRLRAVAN ARERGDGLPG ANTGFGTPSP EDGFEAPVGT
     APADDFADFG WLDEIPRSPG DYVSPRDLAS PGTGGPRSGP YGPSHAVTPH RSPTRTPESR
     AVVLAAADPA NAYGAALPWP EPPTGAGHKA GRKAGSLVVL VDGELTLYME RGGKTLLAWP
     EDPDAKATDD PRLQSAAEAL ATAARAGSLG TVTVERINGT PALTSPIGTL LEGSGFIATP
     RGLRLRA
//