ID A0A0F5ZU25_9GAMM Unreviewed; 456 AA.
AC A0A0F5ZU25;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Multidrug resistance protein NorM {ECO:0000256|ARBA:ARBA00013489};
DE AltName: Full=Multidrug-efflux transporter {ECO:0000256|ARBA:ARBA00031636};
DE AltName: Full=Na(+)/drug antiporter {ECO:0000256|ARBA:ARBA00030855};
GN ORFNames=RN22_17455 {ECO:0000313|EMBL:KKD59178.1};
OS Grimontia sp. AD028.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Grimontia.
OX NCBI_TaxID=1581149 {ECO:0000313|EMBL:KKD59178.1, ECO:0000313|Proteomes:UP000033732};
RN [1] {ECO:0000313|EMBL:KKD59178.1, ECO:0000313|Proteomes:UP000033732}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AD028 {ECO:0000313|EMBL:KKD59178.1,
RC ECO:0000313|Proteomes:UP000033732};
RA Adrian T.-G.-S., Chan K.-G.;
RT "Genome sequencing of Grimontia sp. AD028.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKD59178.1}.
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DR EMBL; LASY01000079; KKD59178.1; -; Genomic_DNA.
DR RefSeq; WP_046306205.1; NZ_LASY01000079.1.
DR AlphaFoldDB; A0A0F5ZU25; -.
DR PATRIC; fig|1581149.3.peg.4410; -.
DR OrthoDB; 9780160at2; -.
DR Proteomes; UP000033732; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR CDD; cd13131; MATE_NorM_like; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR43298:SF2; FMN_FAD EXPORTER YEEO-RELATED; 1.
DR PANTHER; PTHR43298; MULTIDRUG RESISTANCE PROTEIN NORM-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 53..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 456 AA; 49263 MW; 641C613A66DFBE94 CRC64;
MQNYRLEAKS IIKLGIPVFI AQLAQTSMGF VDTVMAGGVS ATDMAAVAVA TSVWLPSILF
GIGILLAMVP IIAQLNGSGR QAKIPFQVQQ GVYMALMLSV PIALVLYNAG HIVNYMEVEA
ALAEKTIGYL YAVILAVPAF LLFQVLRNLA EGMSLTTPAM IIGFIGLAAN VPLNWIFVYG
KFGAPELGAV GCGVATTIVY WLMLISMFIY IKLNKRLQRV NAFADFSKPD FPALWRIFKM
GLPVAAAIFF EVTLFAVIAL LIAPLGSTVV AAHQIAINFS SMIFMLPMSL GTAVSIRVSH
QLGEKSTEGA ARAAKLGILI GLSTAMITAA LTVIFREPII HLYNSNPEVV AIAANLMLLA
AIYQCTDAIQ VVAAGALRGY KDMRAIFERT FVAYWILGVP IGYVLGMTDW IVEPMGAYGF
WVGIIIGLTS AAILLGIRLR WIRKQPDEFQ LAMAEK
//
