ID A0A0F6TSP7_9GAMM Unreviewed; 640 AA.
AC A0A0F6TSP7;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Aminopeptidase {ECO:0000313|EMBL:AKE52975.1};
GN ORFNames=TQ33_2046 {ECO:0000313|EMBL:AKE52975.1};
OS Kangiella geojedonensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Kangiellales; Kangiellaceae;
OC Kangiella.
OX NCBI_TaxID=914150 {ECO:0000313|EMBL:AKE52975.1, ECO:0000313|Proteomes:UP000034071};
RN [1] {ECO:0000313|EMBL:AKE52975.1, ECO:0000313|Proteomes:UP000034071}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YCS-5 {ECO:0000313|EMBL:AKE52975.1,
RC ECO:0000313|Proteomes:UP000034071};
RA Kim K.M.;
RT "Complete genome sequence of Kangiella geojedonensis strain YCS-5T.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|PIRSR:PIRSR036685-1};
CC Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000256|PIRSR:PIRSR036685-
CC 1};
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DR EMBL; CP010975; AKE52975.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F6TSP7; -.
DR STRING; 914150.TQ33_2046; -.
DR KEGG; kge:TQ33_2046; -.
DR PATRIC; fig|914150.5.peg.2075; -.
DR HOGENOM; CLU_025866_2_0_6; -.
DR OrthoDB; 9789219at2; -.
DR Proteomes; UP000034071; Chromosome.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 2.60.120.380; -; 2.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR045175; M28_fam.
DR InterPro; IPR012189; Pept_M28E_Ap1.
DR InterPro; IPR007280; Peptidase_C_arc/bac.
DR InterPro; IPR007484; Peptidase_M28.
DR PANTHER; PTHR12147:SF26; ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1; 1.
DR PANTHER; PTHR12147; METALLOPEPTIDASE M28 FAMILY MEMBER; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04151; PPC; 2.
DR PIRSF; PIRSF036685; BacLeuNPeptidase; 2.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000313|EMBL:AKE52975.1};
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR036685-2};
KW Hydrolase {ECO:0000313|EMBL:AKE52975.1};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR036685-1};
KW Protease {ECO:0000313|EMBL:AKE52975.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000034071};
KW Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|PIRSR:PIRSR036685-1}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..640
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002510646"
FT DOMAIN 209..393
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 449..512
FT /note="Peptidase C-terminal archaeal/bacterial"
FT /evidence="ECO:0000259|Pfam:PF04151"
FT DOMAIN 558..624
FT /note="Peptidase C-terminal archaeal/bacterial"
FT /evidence="ECO:0000259|Pfam:PF04151"
FT BINDING 228
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR036685-1"
FT BINDING 246
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR036685-1"
FT BINDING 281
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR036685-1"
FT BINDING 308
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR036685-1"
FT BINDING 385
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR036685-1"
FT DISULFID 352..356
FT /evidence="ECO:0000256|PIRSR:PIRSR036685-2"
SQ SEQUENCE 640 AA; 68696 MW; DA1CB1AADFD82652 CRC64;
MKYLSTGLLI SGVVAGSLVF AQSATADKPS APVTEQSTSE QNVWITLGGD ALETIQSKYQ
STIPIKLSGI IEQKQNNQIA IAQIPESKII ELSKMMHDEH KRCGGFFYHS SQQEAQEYAH
SINQTQAFAA VNYTIDNPDA VNALLGQISS SNLTTTVNTL SNYNNRYYTS STGVDAANWI
KNEWQSIANG RSDIDVQLYN HSNWNQPSVI ATITGTSDPD DIVIVGGHLD SINSSNTSGR
APGADDNASG IAIATESLRA IVETGFKPER TIKLMGYAAE EVGLRGSNEI ANQHKSNNAN
VIGVVQFDMS GYKGSNKDIV FMTDYTNSDQ NQFLADLIDT YLPSIDYAYD QCGYGCSDHA
SWHNKGYPAS MPFEAYMGQH NGDIHTSRDD HFDASHSVNF AKLSVTYLAE LAKGGTGSNP
DPDPPGDNVL ENGVAETGLS ASQGNDIMYT MEVPAGASNI SFDISGGTGD ADLYVRKGAA
PTDSTYDCRP YKNGNNESCS GNGEGTYYVR IKAYSSFSGL ALVGSYDDET APEPDPGTPP
IDETYSNVSV AQGAWARYSQ ELNGDYSSLT VTITGGSGDA DLYVRHGSQP TTSSYDCRPY
KWGNEETCTI NAPQSGTWHI GLRGYNAASG ITLSVQATPQ
//
