ID A0A0F7FGV4_9CREN Unreviewed; 121 AA.
AC A0A0F7FGV4;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Nascent polypeptide-associated complex protein {ECO:0000256|HAMAP-Rule:MF_00814};
GN Name=nac {ECO:0000256|HAMAP-Rule:MF_00814};
GN ORFNames=MA03_00425 {ECO:0000313|EMBL:AKG38059.1};
OS Infirmifilum uzonense.
OC Archaea; Thermoproteota; Thermoprotei; Thermofilales; Thermofilaceae;
OC Infirmifilum.
OX NCBI_TaxID=1550241 {ECO:0000313|EMBL:AKG38059.1, ECO:0000313|Proteomes:UP000067434};
RN [1] {ECO:0000313|EMBL:AKG38059.1, ECO:0000313|Proteomes:UP000067434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1807-2 {ECO:0000313|EMBL:AKG38059.1,
RC ECO:0000313|Proteomes:UP000067434};
RX PubMed=26664700; DOI=10.1186/s40793-015-0105-y;
RA Toshchakov S.V., Korzhenkov A.A., Samarov N.I., Mazunin I.O., Mozhey O.I.,
RA Shmyr I.S., Derbikova K.S., Taranov E.A., Dominova I.N.,
RA Bonch-Osmolovskaya E.A., Patrushev M.V., Podosokorskaya O.A.,
RA Kublanov I.V.;
RT "Complete genome sequence of and proposal of Thermofilum uzonense sp. nov.
RT a novel hyperthermophilic crenarchaeon and emended description of the genus
RT Thermofilum.";
RL Stand. Genomic Sci. 10:122-122(2015).
CC -!- FUNCTION: Contacts the emerging nascent chain on the ribosome.
CC {ECO:0000256|HAMAP-Rule:MF_00814}.
CC -!- SUBUNIT: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.
CC {ECO:0000256|HAMAP-Rule:MF_00814}.
CC -!- SIMILARITY: Belongs to the NAC-alpha family. {ECO:0000256|HAMAP-
CC Rule:MF_00814}.
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DR EMBL; CP009961; AKG38059.1; -; Genomic_DNA.
DR RefSeq; WP_052883381.1; NZ_CP009961.1.
DR AlphaFoldDB; A0A0F7FGV4; -.
DR STRING; 1550241.MA03_00425; -.
DR GeneID; 25400650; -.
DR KEGG; thf:MA03_00425; -.
DR PATRIC; fig|1550241.5.peg.85; -.
DR HOGENOM; CLU_146475_0_0_2; -.
DR OrthoDB; 53273at2157; -.
DR Proteomes; UP000067434; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR CDD; cd14359; UBA_AeNAC; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 2.20.70.30; Nascent polypeptide-associated complex domain; 1.
DR HAMAP; MF_00814; NAC_arch; 1.
DR InterPro; IPR044034; NAC-like_UBA.
DR InterPro; IPR038187; NAC_A/B_dom_sf.
DR InterPro; IPR005231; NAC_arc.
DR InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR NCBIfam; TIGR00264; archaeal-type nascent polypeptide-associated complex protein; 1.
DR Pfam; PF19026; HYPK_UBA; 1.
DR Pfam; PF01849; NAC; 1.
DR SMART; SM01407; NAC; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51151; NAC_AB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927, ECO:0000256|HAMAP-
KW Rule:MF_00814}; Reference proteome {ECO:0000313|Proteomes:UP000067434};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00814};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_00814}.
FT DOMAIN 3..72
FT /note="NAC-A/B"
FT /evidence="ECO:0000259|PROSITE:PS51151"
SQ SEQUENCE 121 AA; 13337 MW; 6681C674E5DD8A17 CRC64;
MKRLSPREQR RLLERMGLSL KDIEGVEEVQ IKLRDKIITI KNPVVQVLEV KGSGKIYQIS
GVEEESPLTV APSSQQLEVS EEDIDLIVAQ TGATREEAKK ALIESGGDIA KAILSLRSSK
V
//
