ID A0A0F7FI55_9CREN Unreviewed; 275 AA.
AC A0A0F7FI55;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=GDP-mannose dehydrogenase {ECO:0000313|EMBL:AKG38457.1};
GN ORFNames=MA03_03035 {ECO:0000313|EMBL:AKG38457.1};
OS Infirmifilum uzonense.
OC Archaea; Thermoproteota; Thermoprotei; Thermofilales; Thermofilaceae;
OC Infirmifilum.
OX NCBI_TaxID=1550241 {ECO:0000313|EMBL:AKG38457.1, ECO:0000313|Proteomes:UP000067434};
RN [1] {ECO:0000313|EMBL:AKG38457.1, ECO:0000313|Proteomes:UP000067434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1807-2 {ECO:0000313|EMBL:AKG38457.1,
RC ECO:0000313|Proteomes:UP000067434};
RX PubMed=26664700; DOI=10.1186/s40793-015-0105-y;
RA Toshchakov S.V., Korzhenkov A.A., Samarov N.I., Mazunin I.O., Mozhey O.I.,
RA Shmyr I.S., Derbikova K.S., Taranov E.A., Dominova I.N.,
RA Bonch-Osmolovskaya E.A., Patrushev M.V., Podosokorskaya O.A.,
RA Kublanov I.V.;
RT "Complete genome sequence of and proposal of Thermofilum uzonense sp. nov.
RT a novel hyperthermophilic crenarchaeon and emended description of the genus
RT Thermofilum.";
RL Stand. Genomic Sci. 10:122-122(2015).
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DR EMBL; CP009961; AKG38457.1; -; Genomic_DNA.
DR RefSeq; WP_052883864.1; NZ_CP009961.1.
DR AlphaFoldDB; A0A0F7FI55; -.
DR STRING; 1550241.MA03_03035; -.
DR GeneID; 25401172; -.
DR KEGG; thf:MA03_03035; -.
DR PATRIC; fig|1550241.5.peg.645; -.
DR HOGENOM; CLU_1080091_0_0_2; -.
DR OrthoDB; 24929at2157; -.
DR Proteomes; UP000067434; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Reference proteome {ECO:0000313|Proteomes:UP000067434}.
FT DOMAIN 158..239
FT /note="UDP-glucose/GDP-mannose dehydrogenase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF00984"
SQ SEQUENCE 275 AA; 31386 MW; 17631C5CFDC1C107 CRC64;
MTKQKILVVG LGEVGGAVYS VARDSGAFEV YGYDINPSLT VNKLEEVPEN LDYLHVAIPF
NEKFLQNVKS YVEALKPKAL IVHSTVAPGT TRRLHGETGL PVAFSPVRGK HPKIKEHLYF
WPKWVSALPK GFADVARSHL EAMGLKVRVS EEEPEALELA KIWETVYRAV MIAAWQEIDR
IARRYGVGLK TIAEFTAEVH SVLHDRPVYY PDFIGGHCLI PNTKIIYKEV PSKLFEFVLE
SNEKRRIELQ DPRVKKEVEQ LRELFLQLTK RDYYA
//
