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Database: UniProt
Entry: A0A0F7HA24_SERFO
LinkDB: A0A0F7HA24_SERFO
Original site: A0A0F7HA24_SERFO 
ID   A0A0F7HA24_SERFO        Unreviewed;       441 AA.
AC   A0A0F7HA24;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   16-JAN-2019, entry version 31.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:AKG69074.1};
GN   ORFNames=AV650_02870 {ECO:0000313|EMBL:ALX92567.1}, WN53_07995
GN   {ECO:0000313|EMBL:AKG69074.1};
OS   Serratia fonticola.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=47917 {ECO:0000313|EMBL:AKG69074.1, ECO:0000313|Proteomes:UP000034699};
RN   [1] {ECO:0000313|EMBL:AKG69074.1, ECO:0000313|Proteomes:UP000034699}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 4576 {ECO:0000313|EMBL:AKG69074.1,
RC   ECO:0000313|Proteomes:UP000034699};
RA   Chan K.-G., Ee R.;
RT   "Complete Genome Sequencing of Serratia Fonticola DSM-4576.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ALX92567.1, ECO:0000313|Proteomes:UP000061771}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS2 {ECO:0000313|EMBL:ALX92567.1,
RC   ECO:0000313|Proteomes:UP000061771};
RA   Shin J.-H., Jung B.K., Hong S.-J., Park G.-S.;
RT   "Complete genome sequence of Serratia fonticola GS2.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP011254; AKG69074.1; -; Genomic_DNA.
DR   EMBL; CP013913; ALX92567.1; -; Genomic_DNA.
DR   EnsemblBacteria; AKG69074; AKG69074; WN53_07995.
DR   EnsemblBacteria; ALX92567; ALX92567; AV650_02870.
DR   KEGG; sfg:AV650_02870; -.
DR   KEGG; sfw:WN53_07995; -.
DR   PATRIC; fig|47917.8.peg.1654; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   Proteomes; UP000034699; Chromosome.
DR   Proteomes; UP000061771; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034699,
KW   ECO:0000313|Proteomes:UP000061771};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034699}.
FT   DOMAIN      138    340       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      349    418       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     146    153       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      300    320       {ECO:0000256|SAM:Coils}.
FT   COILED      418    438       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   441 AA;  49673 MW;  CA31CF64E0D51D45 CRC64;
     MWIRPLQAEL SDNTLALYAP NRFVLDWVRD KYLNNINGLL NDFCGTDAPL LRFEVGSKPL
     TQTLSQPVMA SVNSAPVAPV VRTAAPSRPS WDNAAPPPEL SYRSNVNPKH TFDNFVEGKS
     NQLARAAARQ VADNPGGAYN PLFLYGGTGL GKTHLLHAVG NGIMARKANA KVVYMHSERF
     VQDMVKALQN NAIEEFKRYY RSVDALLIDD IQFFANKERS QEEFFHTFNA LLEGNQQIIL
     TSDRYPKEIN GVEDRLKSRF GWGLTVAIEP PELETRVAIL MKKADENDIR LPGEVAFFIA
     KRLRSNVREL EGALNRVIAN ANFTGRAITI DFVREALRDL LALQEKLVTI DNIQKTVAEY
     YKIKIADLLS KRRSRSVARP RQMAMALAKE LTNHSLPEIG DAFGGRDHTT VLHACRKIEQ
     LREESHDIKE DFSNLIRTLS S
//
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