ID A0A0F7HD65_SERFO Unreviewed; 394 AA.
AC A0A0F7HD65;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Purine ribonucleoside efflux pump nepI {ECO:0000313|EMBL:VTR52699.1};
DE SubName: Full=Transporter {ECO:0000313|EMBL:AKG70549.1};
GN Name=nepI_3 {ECO:0000313|EMBL:VTR52699.1};
GN ORFNames=NCTC12965_06422 {ECO:0000313|EMBL:VTR52699.1}, WN53_16330
GN {ECO:0000313|EMBL:AKG70549.1};
OS Serratia fonticola.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=47917 {ECO:0000313|EMBL:AKG70549.1, ECO:0000313|Proteomes:UP000034699};
RN [1] {ECO:0000313|EMBL:AKG70549.1, ECO:0000313|Proteomes:UP000034699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4576 {ECO:0000313|EMBL:AKG70549.1,
RC ECO:0000313|Proteomes:UP000034699};
RA Chan K.-G., Ee R.;
RT "Complete Genome Sequencing of Serratia Fonticola DSM-4576.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:VTR52699.1, ECO:0000313|Proteomes:UP000358076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12965 {ECO:0000313|EMBL:VTR52699.1,
RC ECO:0000313|Proteomes:UP000358076};
RG Pathogen Informatics;
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP011254; AKG70549.1; -; Genomic_DNA.
DR EMBL; CABEEZ010000126; VTR52699.1; -; Genomic_DNA.
DR RefSeq; WP_024485354.1; NZ_SUPV01000047.1.
DR AlphaFoldDB; A0A0F7HD65; -.
DR GeneID; 30321742; -.
DR KEGG; sfw:WN53_16330; -.
DR PATRIC; fig|47917.8.peg.3373; -.
DR Proteomes; UP000034699; Chromosome.
DR Proteomes; UP000358076; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17324; MFS_NepI_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR43124:SF3; INNER MEMBRANE TRANSPORT PROTEIN YDHP; 1.
DR PANTHER; PTHR43124; PURINE EFFLUX PUMP PBUE; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000034699};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..387
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 394 AA; 40856 MW; 04F921429AED0651 CRC64;
MLNNKDKPAS SPWLAIFSLT VACFVMVTTE FLPIGLLTNI APSLDVSTGK AGLMVTIPGV
VAAVAAPVLS LLSGRLDRRL LMLGLSALLI ISNLVSALAV NFPMMLLGRV LLGVCVGGFW
SFAANYGRHL VPVASQGRAT ALILSGISVG AVCGVPAGAL IGDLFGWRAA FFGSSVLAGI
VLLAQMRLLT SVPASRPVTP SDLLSPLRLP MARIGLIAIV LLFVGHFAAY TYLRPLLQQV
FVLSPSAISL QLLAYGAIGL LGTFLGERLA EHSLRATFIL ITAMLASILI VSPFLSGIPG
ATLMVLVWGL AFGAVPVCAT NWMFAAVPQA PEAGQALLVS VIQIALASGA LLGGEVVDWQ
GVSSAMLFGG ALILSAMLVF GWSLRSGMIS VKQP
//
