ID A0A0F7HFN6_SERFO Unreviewed; 162 AA.
AC A0A0F7HFN6;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Type II secretion system protein M {ECO:0000256|PIRNR:PIRNR006291};
DE Short=T2SS protein M {ECO:0000256|PIRNR:PIRNR006291};
DE AltName: Full=General secretion pathway protein M {ECO:0000256|PIRNR:PIRNR006291};
GN Name=epsM {ECO:0000313|EMBL:VTR57788.1};
GN ORFNames=NCTC12965_07534 {ECO:0000313|EMBL:VTR57788.1}, WN53_25235
GN {ECO:0000313|EMBL:AKG72158.1};
OS Serratia fonticola.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=47917 {ECO:0000313|EMBL:AKG72158.1, ECO:0000313|Proteomes:UP000034699};
RN [1] {ECO:0000313|EMBL:AKG72158.1, ECO:0000313|Proteomes:UP000034699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4576 {ECO:0000313|EMBL:AKG72158.1,
RC ECO:0000313|Proteomes:UP000034699};
RA Chan K.-G., Ee R.;
RT "Complete Genome Sequencing of Serratia Fonticola DSM-4576.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:VTR57788.1, ECO:0000313|Proteomes:UP000358076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC12965 {ECO:0000313|EMBL:VTR57788.1,
RC ECO:0000313|Proteomes:UP000358076};
RG Pathogen Informatics;
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Inner membrane component of the type II secretion system
CC required for the energy-dependent secretion of extracellular factors
CC such as proteases and toxins from the periplasm.
CC {ECO:0000256|PIRNR:PIRNR006291}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004377}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004377}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the GSP M family.
CC {ECO:0000256|ARBA:ARBA00010637, ECO:0000256|PIRNR:PIRNR006291}.
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DR EMBL; CP011254; AKG72158.1; -; Genomic_DNA.
DR EMBL; CABEEZ010000148; VTR57788.1; -; Genomic_DNA.
DR RefSeq; WP_024486645.1; NZ_CP011254.1.
DR AlphaFoldDB; A0A0F7HFN6; -.
DR STRING; 47917.AV650_20960; -.
DR GeneID; 30323491; -.
DR KEGG; sfw:WN53_25235; -.
DR PATRIC; fig|47917.8.peg.5278; -.
DR Proteomes; UP000034699; Chromosome.
DR Proteomes; UP000358076; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015627; C:type II protein secretion system complex; IEA:InterPro.
DR GO; GO:0015628; P:protein secretion by the type II secretion system; IEA:InterPro.
DR Gene3D; 3.30.1360.100; General secretion pathway protein M, EpsM; 1.
DR InterPro; IPR007690; T2SS_GspM.
DR InterPro; IPR023229; T2SS_M_periplasmic_sf.
DR Pfam; PF04612; T2SSM; 1.
DR PIRSF; PIRSF006291; GspM; 1.
DR SUPFAM; SSF103054; General secretion pathway protein M, EpsM; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|PIRNR:PIRNR006291};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR006291};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006291};
KW Protein transport {ECO:0000256|PIRNR:PIRNR006291};
KW Reference proteome {ECO:0000313|Proteomes:UP000034699};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR006291}.
FT TRANSMEM 17..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 162 AA; 18750 MW; CA7C39B9F843C2D9 CRC64;
MNELKHRWLQ LSLRERGLVL GCGVLVIVSL CYYALWLPWQ QQASQWQRTI AREQNTVEWM
LQQAPRLRQQ GMQPIQEPPL SLSARVAQSA AAQNMNITRM QPQGERLAVT LEPGDFNALM
LWITQLEKRY SVRIVALEVA MRPDKPGWVT VNKLMLERSD GR
//
