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Database: UniProt
Entry: A0A0F7HH44_9STAP
LinkDB: A0A0F7HH44_9STAP
Original site: A0A0F7HH44_9STAP 
ID   A0A0F7HH44_9STAP        Unreviewed;       443 AA.
AC   A0A0F7HH44;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   20-JUN-2018, entry version 24.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AAT16_00185 {ECO:0000313|EMBL:AKG72777.1};
OS   Salinicoccus halodurans.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Salinicoccus.
OX   NCBI_TaxID=407035 {ECO:0000313|EMBL:AKG72777.1, ECO:0000313|Proteomes:UP000034029};
RN   [1] {ECO:0000313|Proteomes:UP000034029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H3B36 {ECO:0000313|Proteomes:UP000034029};
RA   Ma Y., Jiang K., Xue Y.;
RT   "Complete genome sequence of Salinicoccus halodurans strain H3B36,
RT   isolated from the Qaidam basin of China.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00747961}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP011366; AKG72777.1; -; Genomic_DNA.
DR   RefSeq; WP_046788973.1; NZ_FOTB01000003.1.
DR   EnsemblBacteria; AKG72777; AKG72777; AAT16_00185.
DR   KEGG; shv:AAT16_00185; -.
DR   PATRIC; fig|407035.3.peg.47; -.
DR   KO; K02313; -.
DR   Proteomes; UP000034029; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000034029};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00747973};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00748008};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034029}.
FT   DOMAIN      140    268       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      352    421       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     148    155       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      421    441       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   443 AA;  50807 MW;  B6953A2B8022A309 CRC64;
     MSSLNEIWEN TLKGIEEQIA TASYSTWFKE TTMTHLDNDK AVVKAESQFQ RDWLEKNYSQ
     LIQEKLYEVM GEKPDIHVVT EDEQTRGMAT PVSQEQEEMT EFPVHNQLNV NNTFETFVIG
     NGNRFSHAAS LAVAEAPAKA YNPLFIYGGV GLGKTHLMHA IGHYVLEHRP NAKVAYLSSE
     KFTNEFINSI RDNKTEAFRN RYRNVDVLLI DDIQFLAGKE STQEEFFHTF NALHEDNKQI
     VISSDRTPKE IPTLEDRLRS RFEWGLITDI TPPDLETRIA ILRKKCEEEE VEIPNEAMIY
     IANHIQTNIR ELEGALTRVA AYSKLVNQPL TPEMVSEALK DLVTQSSSKK ITITDIQEAV
     AGFYDIQIEE FSSKKRTKSI AFPRQIAMYL ARELTDYSLP KIGEVFGGRD HSTVIHAHEK
     ISKMLNQDEI FKQELEQIEN KIS
//
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