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Database: UniProt
Entry: A0A0F7HMB2_9STAP
LinkDB: A0A0F7HMB2_9STAP
Original site: A0A0F7HMB2_9STAP 
ID   A0A0F7HMB2_9STAP        Unreviewed;       144 AA.
AC   A0A0F7HMB2;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=Peroxide-responsive repressor PerR {ECO:0000256|ARBA:ARBA00040445};
GN   ORFNames=AAT16_09820 {ECO:0000313|EMBL:AKG75327.1};
OS   Salinicoccus halodurans.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Salinicoccus.
OX   NCBI_TaxID=407035 {ECO:0000313|EMBL:AKG75327.1, ECO:0000313|Proteomes:UP000034029};
RN   [1] {ECO:0000313|EMBL:AKG75327.1, ECO:0000313|Proteomes:UP000034029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H3B36 {ECO:0000313|EMBL:AKG75327.1,
RC   ECO:0000313|Proteomes:UP000034029};
RX   PubMed=26634017;
RA   Jiang K., Xue Y., Ma Y.;
RT   "Complete genome sequence of Salinicoccus halodurans H3B36, isolated from
RT   the Qaidam Basin in China.";
RL   Stand. Genomic Sci. 10:116-116(2015).
RN   [2] {ECO:0000313|Proteomes:UP000034029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H3B36 {ECO:0000313|Proteomes:UP000034029};
RA   Ma Y., Jiang K., Xue Y.;
RT   "Complete genome sequence of Salinicoccus halodurans strain H3B36, isolated
RT   from the Qaidam basin of China.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602481-2};
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602481-2};
CC       Note=Binds 1 Mn(2+) or Fe(2+) ion per subunit.
CC       {ECO:0000256|PIRSR:PIRSR602481-2};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602481-1};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000256|PIRSR:PIRSR602481-1};
CC   -!- SIMILARITY: Belongs to the Fur family. {ECO:0000256|ARBA:ARBA00007957}.
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DR   EMBL; CP011366; AKG75327.1; -; Genomic_DNA.
DR   RefSeq; WP_046791535.1; NZ_FOTB01000005.1.
DR   AlphaFoldDB; A0A0F7HMB2; -.
DR   STRING; 407035.AAT16_09820; -.
DR   KEGG; shv:AAT16_09820; -.
DR   PATRIC; fig|407035.3.peg.1998; -.
DR   OrthoDB; 8659436at2; -.
DR   Proteomes; UP000034029; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd07153; Fur_like; 1.
DR   Gene3D; 3.30.1490.190; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR002481; FUR.
DR   InterPro; IPR043135; Fur_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR33202:SF8; PEROXIDE-RESPONSIVE REPRESSOR PERR; 1.
DR   PANTHER; PTHR33202; ZINC UPTAKE REGULATION PROTEIN; 1.
DR   Pfam; PF01475; FUR; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Iron {ECO:0000256|PIRSR:PIRSR602481-2};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR602481-1};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PIRSR:PIRSR602481-1}.
FT   BINDING         97
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT   BINDING         100
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT   BINDING         112
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-2"
FT   BINDING         129
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-2"
FT   BINDING         137
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT   BINDING         140
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
SQ   SEQUENCE   144 AA;  16494 MW;  438A60190A590E2D CRC64;
     MDANEQFTDS IDALKKTGVR ITPQRKAVLK YMIETEEHPT ADDIFKALSD EYPNMSVATI
     YNNLKLFKDT GLVKELTYGD SSSRFDFITD THYHIICSNC GKITDFHYPG LEEVEQLAGS
     VTEYDVSHHR LEIYGLCPEC REQM
//
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