ID A0A0F7KPZ8_9SPHN Unreviewed; 677 AA.
AC A0A0F7KPZ8;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Beta-lactam-inducible penicillin-binding protein {ECO:0000313|EMBL:AKH41629.1};
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:MBB5733091.1};
GN Name=pbp {ECO:0000313|EMBL:AKH41629.1};
GN ORFNames=FHS61_002117 {ECO:0000313|EMBL:MBB5733091.1}, WYH_00571
GN {ECO:0000313|EMBL:AKH41629.1};
OS Croceibacterium atlanticum.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Croceibacterium.
OX NCBI_TaxID=1267766 {ECO:0000313|EMBL:AKH41629.1, ECO:0000313|Proteomes:UP000034392};
RN [1] {ECO:0000313|EMBL:AKH41629.1, ECO:0000313|Proteomes:UP000034392}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=26DY36 {ECO:0000313|EMBL:AKH41629.1,
RC ECO:0000313|Proteomes:UP000034392};
RA Wu Y.-H., Cheng H., Wu X.-W.;
RT "The complete genome of Altererythrobacter atlanticus strain 26DY36.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MBB5733091.1, ECO:0000313|Proteomes:UP000556014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100738 {ECO:0000313|EMBL:MBB5733091.1,
RC ECO:0000313|Proteomes:UP000556014};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; CP011452; AKH41629.1; -; Genomic_DNA.
DR EMBL; JACIJL010000004; MBB5733091.1; -; Genomic_DNA.
DR RefSeq; WP_046902626.1; NZ_JACIJL010000004.1.
DR AlphaFoldDB; A0A0F7KPZ8; -.
DR STRING; 1267766.WYH_00571; -.
DR KEGG; aay:WYH_00571; -.
DR PATRIC; fig|1267766.3.peg.577; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000034392; Chromosome.
DR Proteomes; UP000556014; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000034392};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..233
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 266..586
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 645..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 677 AA; 73342 MW; BDCCFA537DC04D48 CRC64;
MALNKFTSSS LRQSFDRRSF IVGGIQGGIG VLLAARMGYI AVAENEKYEM EAESNRVNLS
LIPPRRGWIL DRNGAPLASN RADFRIDIFP DRLTDADATV EQLSDLLNFS PAEKEDLRDR
LDKSAGFQPV PVASGLEYET FAAVSVRLPD MHGVVPQRGF SRYYPTGASV GHLIGYVGPA
SREEYEADPS PLLVTPGFKV GKDGLEKQFE QTLRGEPGAR RVEVTASGRI VRDLETREDV
QGNAIRLTID GPLQDYAARR IGLESGSVVV IDCLTGDLLC MASMPSFDPN SFSDGIGRVE
YQMLRDDERV PLRNKVLKGL YPPGSTVKPM VAMSFLEAGL DPHAATTCTG GLRVGNRVFH
CWQRGGHGRV DMAKGIYQSC DVYFYHFAQQ LGMDVIAPMA RRCGMGQEFP LPVTSQFYGT
VPDPAWKLQK YGQKWQAFDT VNATIGQGYM LANPLQLAVM SARLATGNKV MPRLLIDGTR
PKFDTMNFHG DHVQVIQNAM SDVVNGPGTA GRARLPIDDV LLAGKTGTAQ VVSLSVASGK
SGPWKYRDHG LFISFAPFDN PRYACAVVIE HGGGSSAAYP IARDVMTFLF DPAKGLDALH
KLEEQWGGTA QERLAAQYAQ YATAAGVDLP PAPADPVAVA REVDAEARAA AQPATAATEA
VTPRPEPEAN TAARTGE
//
