ID A0A0F7KXJ9_9SPHN Unreviewed; 546 AA.
AC A0A0F7KXJ9;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Acetolactate synthase {ECO:0000313|EMBL:AKH43535.1, ECO:0000313|EMBL:MBB5731756.1};
DE EC=2.2.1.6 {ECO:0000313|EMBL:AKH43535.1, ECO:0000313|EMBL:MBB5731756.1};
GN Name=alsS {ECO:0000313|EMBL:AKH43535.1};
GN ORFNames=FHS61_000760 {ECO:0000313|EMBL:MBB5731756.1}, WYH_02505
GN {ECO:0000313|EMBL:AKH43535.1};
OS Croceibacterium atlanticum.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Croceibacterium.
OX NCBI_TaxID=1267766 {ECO:0000313|EMBL:AKH43535.1, ECO:0000313|Proteomes:UP000034392};
RN [1] {ECO:0000313|EMBL:AKH43535.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=26DY36 {ECO:0000313|EMBL:AKH43535.1};
RA Wu Y.-H., Cheng H., Wu X.-W.;
RT "The complete genome of Altererythrobacter atlanticus strain 26DY36.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MBB5731756.1, ECO:0000313|Proteomes:UP000556014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100738 {ECO:0000313|EMBL:MBB5731756.1,
RC ECO:0000313|Proteomes:UP000556014};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TPP enzyme family.
CC {ECO:0000256|ARBA:ARBA00007812, ECO:0000256|RuleBase:RU362132}.
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DR EMBL; CP011452; AKH43535.1; -; Genomic_DNA.
DR EMBL; JACIJL010000002; MBB5731756.1; -; Genomic_DNA.
DR RefSeq; WP_046904066.1; NZ_JACIJL010000002.1.
DR AlphaFoldDB; A0A0F7KXJ9; -.
DR STRING; 1267766.WYH_02505; -.
DR KEGG; aay:WYH_02505; -.
DR PATRIC; fig|1267766.3.peg.2536; -.
DR OrthoDB; 4494979at2; -.
DR Proteomes; UP000034392; Chromosome.
DR Proteomes; UP000556014; Unassembled WGS sequence.
DR GO; GO:0003984; F:acetolactate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd07035; TPP_PYR_POX_like; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom.
DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR InterPro; IPR045229; TPP_enz.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR18968:SF129; ACETOLACTATE SYNTHASE; 1.
DR PANTHER; PTHR18968; THIAMINE PYROPHOSPHATE ENZYMES; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR Pfam; PF00205; TPP_enzyme_M; 1.
DR Pfam; PF02776; TPP_enzyme_N; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000034392};
KW Thiamine pyrophosphate {ECO:0000256|RuleBase:RU362132};
KW Transferase {ECO:0000313|EMBL:AKH43535.1}.
FT DOMAIN 1..116
FT /note="Thiamine pyrophosphate enzyme N-terminal TPP-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02776"
FT DOMAIN 186..319
FT /note="Thiamine pyrophosphate enzyme central"
FT /evidence="ECO:0000259|Pfam:PF00205"
FT DOMAIN 378..523
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 546 AA; 58835 MW; DDD9ACE0A8374A3C CRC64;
MKASDLMVAA LEAEGVEYVF AVPGEENLDL LESLRTSTIT LVLARHEQGA GFMAATYGRL
TGKAGVCLAT LGPGATNLTT PAAYAALGAF PLVIITGQKP IKTSKQAQFQ IVDVVSLFTP
LCKASTQIVN GNRIPSLVRE GFRLAQEERP GAVLLELPED IAEEQTVEPV IPPHDRRYAV
AGDAALDEAA RRILAAQRPL LLIGAGANRR CASKALRKFV SDTGFPFFDT QMGKGVVDED
SELYLGTAAL SSGDYVHCAI EKADLIVNIG HDVVEKPPFF MEPGGQTVIH INYKAAEVDQ
VYFPQLEVIG DIAGSVERLG SRLDGKLQCD RGYYTALHRE IASHISETSD DERFPMVPQR
VVADVRSVMA RDDIVALDNG IYKIWFARNY IANEPGTILL DNALATMGAG LPSAMVAAML
SPGQRVLAVC GDGGFMMNSQ ELETAVRLGL NLVVLVLNDA AYGMIRWKQD QLGFPDYGLT
FSNPDFVTYA QSYGATGHRV ERSADLVSVL NAAFEAGGVH LVDLPVDYSE NKKVLIDELG
AKVCEL
//
