ID A0A0F7M181_9GAMM Unreviewed; 708 AA.
AC A0A0F7M181;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=ATP-dependent DNA helicase DinG {ECO:0000256|HAMAP-Rule:MF_02205};
DE EC=3.6.4.12 {ECO:0000256|HAMAP-Rule:MF_02205};
GN Name=dinG {ECO:0000256|HAMAP-Rule:MF_02205};
GN ORFNames=IMCC21906_01047 {ECO:0000313|EMBL:AKH68726.1};
OS Spongiibacter sp. IMCC21906.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC Spongiibacteraceae; Spongiibacter.
OX NCBI_TaxID=1620392 {ECO:0000313|EMBL:AKH68726.1, ECO:0000313|Proteomes:UP000035013};
RN [1] {ECO:0000313|EMBL:AKH68726.1, ECO:0000313|Proteomes:UP000035013}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC21906 {ECO:0000313|EMBL:AKH68726.1,
RC ECO:0000313|Proteomes:UP000035013};
RA Cho J.-C., Yang S.-J., Kang I.;
RT "Complete genome sequence of IMCC21906 belonging to the
RT Gammaproteobacteria.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent ATPase and 5'-3' DNA helicase.
CC {ECO:0000256|HAMAP-Rule:MF_02205}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_02205};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_02205};
CC Note=Binds 1 [4Fe-4S] cluster. {ECO:0000256|HAMAP-Rule:MF_02205};
CC -!- SIMILARITY: Belongs to the helicase family. DinG subfamily. Type 1 sub-
CC subfamily. {ECO:0000256|HAMAP-Rule:MF_02205}.
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DR EMBL; CP011477; AKH68726.1; -; Genomic_DNA.
DR RefSeq; WP_047011271.1; NZ_CP011477.1.
DR AlphaFoldDB; A0A0F7M181; -.
DR STRING; 1620392.IMCC21906_01047; -.
DR KEGG; spoi:IMCC21906_01047; -.
DR PATRIC; fig|1620392.3.peg.1098; -.
DR OrthoDB; 9805194at2; -.
DR Proteomes; UP000035013; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_02205; DinG_proteobact; 1.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR039000; DinG_proteobact.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR PANTHER; PTHR11472:SF59; ATP-DEPENDENT DNA HELICASE DING; 1.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|HAMAP-Rule:MF_02205};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_02205}; DNA-binding {ECO:0000256|HAMAP-Rule:MF_02205};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|HAMAP-Rule:MF_02205};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_02205};
KW Iron {ECO:0000256|HAMAP-Rule:MF_02205};
KW Iron-sulfur {ECO:0000256|HAMAP-Rule:MF_02205};
KW Metal-binding {ECO:0000256|HAMAP-Rule:MF_02205};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_02205}; Reference proteome {ECO:0000313|Proteomes:UP000035013}.
FT DOMAIN 15..330
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT BINDING 129
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02205"
FT BINDING 203
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02205"
FT BINDING 208
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02205"
FT BINDING 214
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02205"
SQ SEQUENCE 708 AA; 77774 MW; EAB6EB4644BF5FCC CRC64;
MLSEDLKQEI QTAYRSFLSA KSLRPRTGQR LMVAHIARML GSIKRNQEGI RSAGDHLCAI
EAGTGTGKTL AYTLAAIPIA KARDKTLVIA TATIALQEQI LFRDLPDILQ HSGLDFSVSL
AKGRRRYLCL SKLDQILSGG DAQTLPLLNL DDKQSSPDDA NLGLYTQLAE NLATGQWSGD
RDAWDTVIDD QSWSRVTTDH AQCTGRRCSH VKQCSFFKAR DSMGQADVVV ANHDLVLADL
ALGGGAILPP PEDCIYIFDE AHHLPDKVIN HFSANVRLGA TERWFEQAER SLAAIISLPA
LDLSLRGPME TLMGTLSQSR KAMGPLRPML EALLEEASAA GLSRGYRFVD GLIPEALASQ
SRDLNQGFSE LVSQAEQLLD KVQEGLDKNH FKAPHEEVEQ WLTTLSAIRY RCQAGALLWS
SYASDASKEK PPQARWLAMV ETGQGLLDIE LNASPILAAN ALRYSLWSRC YGAVMTSATL
TALGSFNRFS MRAGLASDAS FEVVPSPFNH VEAGELYIPK MDCDAGDAVA HTEALINMLP
TLLNPEEGSL VLFASRKQMR GVYEGLPSEW QARILAQDSL PKHEILSRHR EVVDKGSGSV
IFGLASFAEG VDLPGNYCSH VIIAKIPFSV PEDPVEEALA EWISRNNGNP FMEITVPDAA
VRLVQASGRL LRKESDRGRI TILDRRIVSR HYGRKILMSM PPYQHNIE
//
