ID A0A0F7N837_9ACTN Unreviewed; 332 AA.
AC A0A0F7N837;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Caunorubicin/doxorubicin resistance ATP-binding protein {ECO:0000313|EMBL:AKH83574.1};
GN ORFNames=AA958_16675 {ECO:0000313|EMBL:AKH83574.1};
OS Streptomyces sp. CNQ-509.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=444103 {ECO:0000313|EMBL:AKH83574.1, ECO:0000313|Proteomes:UP000034283};
RN [1] {ECO:0000313|EMBL:AKH83574.1, ECO:0000313|Proteomes:UP000034283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CNQ-509 {ECO:0000313|EMBL:AKH83574.1,
RC ECO:0000313|Proteomes:UP000034283};
RA Ruckert C., Albersmeier A., Leipoldt F., Winkler A., Zeyhle P.,
RA Kalinowski J., Heide L., Kaysser L.;
RT "Complete Genome Sequence of Streptomyces sp. CNQ-509, a Prolific Producer
RT of Meroterpenoid Chemistry.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP011492; AKH83574.1; -; Genomic_DNA.
DR RefSeq; WP_047016879.1; NZ_CP011492.1.
DR AlphaFoldDB; A0A0F7N837; -.
DR STRING; 444103.AA958_16675; -.
DR KEGG; strc:AA958_16675; -.
DR PATRIC; fig|444103.5.peg.3509; -.
DR OrthoDB; 9804819at2; -.
DR Proteomes; UP000034283; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043215; P:daunorubicin transport; IEA:InterPro.
DR GO; GO:1900753; P:doxorubicin transport; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR005894; DrrA.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01188; drrA; 1.
DR PANTHER; PTHR42711; ABC TRANSPORTER ATP-BINDING PROTEIN; 1.
DR PANTHER; PTHR42711:SF18; DOXORUBICIN RESISTANCE ATP-BINDING PROTEIN DRRA; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:AKH83574.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000034283}.
FT DOMAIN 10..240
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 332 AA; 34475 MW; DCF5D7C7BB5648C8 CRC64;
MTNDPSGLAI ETSGLVKVFG ETRAVDGVDL AVPRGTVYGV LGPNGAGKTT TVKMLATLLR
PDGGEARIFG KDVVRDANAV RSRVSLTGQY ASVDEDLTGT ENLVLLGRLL GHRPAAARVR
AAQLLEAFGL SEAAAKQVKN YSGGMRRRID IAASILNTPD LLFLDEPTTG LDPRSRNQVW
DIVRAVVAQG TTVLLTTQYL DEADQLASRI AVIDHGKVIA EGTKGELKAS VGAGSVHLRL
RDAAQRAEAV ALLETALAGA QVQLEPDPVA LTARVGNGDG SAAAAQAAAA LAELARADIT
VDNFSLGQPS LDEVFLALTD RPAGAETQEA AA
//
