ID A0A0F7N9W2_9ACTN Unreviewed; 333 AA.
AC A0A0F7N9W2;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:AKH84831.1};
GN ORFNames=AA958_24400 {ECO:0000313|EMBL:AKH84831.1};
OS Streptomyces sp. CNQ-509.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=444103 {ECO:0000313|EMBL:AKH84831.1, ECO:0000313|Proteomes:UP000034283};
RN [1] {ECO:0000313|EMBL:AKH84831.1, ECO:0000313|Proteomes:UP000034283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CNQ-509 {ECO:0000313|EMBL:AKH84831.1,
RC ECO:0000313|Proteomes:UP000034283};
RA Ruckert C., Albersmeier A., Leipoldt F., Winkler A., Zeyhle P.,
RA Kalinowski J., Heide L., Kaysser L.;
RT "Complete Genome Sequence of Streptomyces sp. CNQ-509, a Prolific Producer
RT of Meroterpenoid Chemistry.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP011492; AKH84831.1; -; Genomic_DNA.
DR RefSeq; WP_047018083.1; NZ_CP011492.1.
DR AlphaFoldDB; A0A0F7N9W2; -.
DR STRING; 444103.AA958_24400; -.
DR KEGG; strc:AA958_24400; -.
DR PATRIC; fig|444103.5.peg.5143; -.
DR OrthoDB; 582216at2; -.
DR Proteomes; UP000034283; Chromosome.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031725; ASMT_dimerisation.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF16864; Dimerisation2; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:AKH84831.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000034283};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:AKH84831.1}.
FT DOMAIN 11..90
FT /note="Acetylserotonin O-methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF16864"
FT DOMAIN 166..313
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
SQ SEQUENCE 333 AA; 35838 MW; 41EE719A5B5C822F CRC64;
MTDGRPNSDR VLRLITGYWA TGIVGTAAKY ALFTHIEDGA RTVDALAARA ELSVRGTQAL
LDGLVSLDLV ERRGGEYHNT EEAATYLVDH LPTSLTSFAQ FKMGHMGSLT DLPEVVRAGG
PLSTSVVEVA DNPHWEALVT ALAASSVPAT EIAAEALGIA GAGEVSILDI GGGSGIYCGT
FLELNPAARA TQLDWAPINA IARRLLAERG VGERVDYIDG DFHTTEFGTS AYDYVVYSNI
ARQEGPQDNM ALFAKIRAAL KPGGTLIVSD YVVDDDRGGG SKYALQFASE MLLKSRHGST
WRRADYHEWL VKSEFEEITF QPTPSPATLI FAR
//
