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Database: UniProt
Entry: A0A0F7NBD8_9ACTN
LinkDB: A0A0F7NBD8_9ACTN
Original site: A0A0F7NBD8_9ACTN 
ID   A0A0F7NBD8_9ACTN        Unreviewed;       320 AA.
AC   A0A0F7NBD8;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=RNA polymerase sigma 70 {ECO:0000313|EMBL:AKH84783.1};
GN   ORFNames=AA958_24095 {ECO:0000313|EMBL:AKH84783.1};
OS   Streptomyces sp. CNQ-509.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=444103 {ECO:0000313|EMBL:AKH84783.1, ECO:0000313|Proteomes:UP000034283};
RN   [1] {ECO:0000313|EMBL:AKH84783.1, ECO:0000313|Proteomes:UP000034283}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CNQ-509 {ECO:0000313|EMBL:AKH84783.1,
RC   ECO:0000313|Proteomes:UP000034283};
RA   Ruckert C., Albersmeier A., Leipoldt F., Winkler A., Zeyhle P.,
RA   Kalinowski J., Heide L., Kaysser L.;
RT   "Complete Genome Sequence of Streptomyces sp. CNQ-509, a Prolific Producer
RT   of Meroterpenoid Chemistry.";
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic core
CC       formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1
CC       omega subunit) to form the RNA polymerase holoenzyme that can initiate
CC       transcription. {ECO:0000256|ARBA:ARBA00011344}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|ARBA:ARBA00010641}.
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DR   EMBL; CP011492; AKH84783.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F7NBD8; -.
DR   STRING; 444103.AA958_24095; -.
DR   KEGG; strc:AA958_24095; -.
DR   PATRIC; fig|444103.5.peg.5078; -.
DR   OrthoDB; 3211555at2; -.
DR   Proteomes; UP000034283; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR   Gene3D; 1.10.1740.10; -; 1.
DR   Gene3D; 3.10.450.50; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR30173:SF36; ECF-FAMILY RNA POLYMERASE SIGMA FACTOR-RELATED; 1.
DR   PANTHER; PTHR30173; SIGMA 19 FACTOR; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   SUPFAM; SSF54427; NTF2-like; 1.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000034283};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          21..80
FT                   /note="RNA polymerase sigma-70 region 2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          116..167
FT                   /note="RNA polymerase sigma factor 70 region 4 type 2"
FT                   /evidence="ECO:0000259|Pfam:PF08281"
SQ   SEQUENCE   320 AA;  34818 MW;  B9B3305883AC3AC1 CRC64;
     MERMDGTATD RFDTGRFEDG RARLVSLAYR MLGSVADAED AVQDAYLRWQ AADRRRIEVP
     EAWLTKVLTN LCIDRLRSAR ARRERSVGAW LPEPVLDGDP VLGPADTFEQ RESVSLAVLT
     LMERLSPVQR AVYLLHVTFS YGHAEIAGIL GISESASQQH LHRARRRVTA TRHGGGEADR
     AAALRIAEEF FTAAASGRTE RLVELLTDDA TAISDGAGLT GTMLRYDTPQ RIAAIARAGF
     AASPTKRRFA GGIPAVHSAH VNGGPAILFV VGGKVFGAVT FDLAGGRIAL VRGIADPARL
     GRLNEAWRRY EPGPPVLARW
//
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