ID A0A0F7P8J1_9EURY Unreviewed; 248 AA.
AC A0A0F7P8J1;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=GMP synthase-glutamine amidotransferase domain protein {ECO:0000313|EMBL:AKH97481.1};
DE SubName: Full=GMP synthase-glutamine amidotransferase domainprotein {ECO:0000313|EMBL:ALG81877.1};
DE EC=6.3.5.2 {ECO:0000313|EMBL:AKH97481.1, ECO:0000313|EMBL:ALG81877.1};
GN Name=guaA2 {ECO:0000313|EMBL:AKH97481.1};
GN Synonyms=guaA1 {ECO:0000313|EMBL:ALG81877.1};
GN ORFNames=HLASA_0980 {ECO:0000313|EMBL:ALG81877.1}, HLASF_0991
GN {ECO:0000313|EMBL:AKH97481.1};
OS Halanaeroarchaeum sulfurireducens.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halanaeroarchaeum.
OX NCBI_TaxID=1604004 {ECO:0000313|EMBL:AKH97481.1, ECO:0000313|Proteomes:UP000069906};
RN [1] {ECO:0000313|EMBL:AKH97481.1, ECO:0000313|Proteomes:UP000069906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HSR2 {ECO:0000313|EMBL:AKH97481.1,
RC ECO:0000313|Proteomes:UP000069906};
RX PubMed=25978546;
RA Sorokin D.Y., Kublanov I.V., Gavrilov S.N., Rojo D., Roman P.,
RA Golyshin P.N., Slepak V.Z., Smedile F., Ferrer M., Messina E., La Cono V.,
RA Yakimov M.M.;
RT "Elemental sulfur and acetate can support life of a novel strictly
RT anaerobic haloarchaeon.";
RL ISME J. 0:0-0(2015).
RN [2] {ECO:0000313|Proteomes:UP000060390}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M27-SA2 {ECO:0000313|Proteomes:UP000060390};
RA Messina E., Kublanov I.V., Toshchakov S., Arcadi E., La Spada G.,
RA La Cono V., Yakimov M.M.;
RT "Complete genome sequence of Halanaeroarchaeum sulfurireducens type strain
RT M27-SA2, a sulfate-reducer haloarchaeon from marine anoxic lake Medee.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ALG81877.1, ECO:0000313|Proteomes:UP000060390}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M27-SA2 {ECO:0000313|EMBL:ALG81877.1,
RC ECO:0000313|Proteomes:UP000060390};
RX PubMed=27182430; DOI=10.1186/s40793-016-0155-9;
RA Messina E., Sorokin D.Y., Kublanov I.V., Toshchakov S., Lopatina A.,
RA Arcadi E., Smedile F., La Spada G., La Cono V., Yakimov M.M.;
RT "Complete genome sequence of 'Halanaeroarchaeum sulfurireducens' M27-SA2, a
RT sulfur-reducing and acetate-oxidizing haloarchaeon from the deep-sea
RT hypersaline anoxic lake Medee.";
RL Stand. Genomic Sci. 11:35-35(2016).
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DR EMBL; CP008874; AKH97481.1; -; Genomic_DNA.
DR EMBL; CP011564; ALG81877.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F7P8J1; -.
DR STRING; 1604004.HLASA_0980; -.
DR KEGG; hsf:HLASA_0980; -.
DR KEGG; hsu:HLASF_0991; -.
DR PATRIC; fig|1604004.4.peg.1040; -.
DR HOGENOM; CLU_054974_4_1_2; -.
DR Proteomes; UP000060390; Chromosome.
DR Proteomes; UP000069906; Chromosome.
DR GO; GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd01741; GATase1_1; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR044992; ChyE-like.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR017926; GATASE.
DR PANTHER; PTHR42695; GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED; 1.
DR PANTHER; PTHR42695:SF5; GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED; 1.
DR Pfam; PF00117; GATase; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR PROSITE; PS51273; GATASE_TYPE_1; 1.
PE 4: Predicted;
KW Glutamine amidotransferase {ECO:0000256|PROSITE-ProRule:PRU00605,
KW ECO:0000313|EMBL:AKH97481.1}; Ligase {ECO:0000313|EMBL:AKH97481.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000069906};
KW Transferase {ECO:0000313|EMBL:AKH97481.1}.
FT DOMAIN 32..185
FT /note="Glutamine amidotransferase"
FT /evidence="ECO:0000259|Pfam:PF00117"
FT ACT_SITE 95
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 179
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 181
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
SQ SEQUENCE 248 AA; 27802 MW; 3B3347C5359E1C6A CRC64;
MSIETHAFSM DTPRIALLNA GHAAVETRRN FERELDAELV EFNCPEGEFP SSFAFDGCVV
TGSAASVYWD EPWIERLKQW VGEAVAAGLP FLGVCYGHQL LASVLGGEVE DMGEYELGYR
TIHHDGENRL LDGIEEEFTA FTTHSDRVTQ TPPGANVFAR NDYGIQGFRT DRVFAVQFHP
EYDLEMARTI TKKKDLDEER IDAVLATITD ENYRAASETK QLFDNFLAYV ESVQTGRTTV
ESPTPQTD
//
