ID A0A0F7RP69_SERDU Unreviewed; 120 AA.
AC A0A0F7RP69;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Follicle-stimulating hormone beta subunit {ECO:0000313|EMBL:BAR79709.1};
DE SubName: Full=Gonadotropin subunit beta-1-like {ECO:0000313|Ensembl:ENSSDUP00000020445.1};
GN Name=Fshb {ECO:0000313|EMBL:BAR79709.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|EMBL:BAR79709.1};
RN [1] {ECO:0000313|EMBL:BAR79709.1}
RP NUCLEOTIDE SEQUENCE.
RA Nyuji M., Kazeto Y., Izumida D., Tani K., Suzuki H., Hamada K., Mekuchi M.,
RA Gen K., Soyano K., Okuzawa K.;
RT "Greater amberjack Fsh, Lh, and their receptors: Plasma and mRNA profiles
RT during ovarian development.";
RL Gen. Comp. Endocrinol. 255:224-234(2016).
RN [2] {ECO:0000313|Ensembl:ENSSDUP00000020445.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Involved in gametogenesis and steroidogenesis.
CC {ECO:0000256|ARBA:ARBA00003920}.
CC -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
CC {ECO:0000256|ARBA:ARBA00011870}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the glycoprotein hormones subunit beta family.
CC {ECO:0000256|ARBA:ARBA00006552}.
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DR EMBL; LC019038; BAR79709.1; -; mRNA.
DR STRING; 41447.ENSSDUP00000020445; -.
DR Ensembl; ENSSDUT00000020815.1; ENSSDUP00000020445.1; ENSSDUG00000014870.1.
DR GeneTree; ENSGT00940000158152; -.
DR OMA; CAGQCYH; -.
DR OrthoDB; 4234826at2759; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR CDD; cd00069; GHB_like; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR006208; Glyco_hormone_CN.
DR InterPro; IPR001545; Gonadotropin_bsu.
DR PANTHER; PTHR11515; GLYCOPROTEIN HORMONE BETA CHAIN; 1.
DR PANTHER; PTHR11515:SF11; LUTROPIN SUBUNIT BETA; 1.
DR Pfam; PF00007; Cys_knot; 1.
DR SMART; SM00068; GHB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
PE 2: Evidence at transcript level;
KW Hormone {ECO:0000256|ARBA:ARBA00022702};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..120
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040667101"
FT DOMAIN 22..114
FT /note="Glycoprotein hormone subunit beta"
FT /evidence="ECO:0000259|Pfam:PF00007"
SQ SEQUENCE 120 AA; 12928 MW; CA4ADE927886AA27 CRC64;
MQLVVMAAVL AMAEAGQGCS FGCHPTVVNI SVESCAGPEV VRTTICAGQC YHEDPVYISD
YDWPEQKTCN GDWSFEVKHT PGCPVGISYP VARNCKCAAC NEDNMFCGRF LGDVSSCLSF
//
