ID A0A0F7S512_9BASI Unreviewed; 1133 AA.
AC A0A0F7S512;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=HECT-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012485};
DE EC=2.3.2.26 {ECO:0000256|ARBA:ARBA00012485};
GN Name=SSCI07640.1 {ECO:0000313|EMBL:CDW95491.1};
OS Sporisorium scitamineum.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Sporisorium.
OX NCBI_TaxID=49012 {ECO:0000313|EMBL:CDW95491.1, ECO:0000313|Proteomes:UP000242770};
RN [1] {ECO:0000313|Proteomes:UP000242770}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Berkman P.J.;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CCFA01000394; CDW95491.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F7S512; -.
DR STRING; 49012.A0A0F7S512; -.
DR OrthoDB; 1386at2759; -.
DR Proteomes; UP000242770; Unassembled WGS sequence.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR CDD; cd00078; HECTc; 1.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR044611; E3A/B/C-like.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR PANTHER; PTHR45700:SF2; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 795..1133
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT REGION 429..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..444
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 1101
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 1133 AA; 126030 MW; B3D96A4C7FBC9CC6 CRC64;
MSFHFTGAGR TRAPVSLGGI STLLADPVQT AREQRLEREQ QRRKQSASIR IQSQARRILE
SRQTRYQWQL QSRQLLEHLE ADLLSRACLG SAEGLSRLVV ATRILLVSLG PESRALDQSD
AELFLRWIRL VLQSIDGIRL VFLPFKQPSQ NAFDDSWLSL LRLACKHSLR FLAKAAVSRT
QDASATPTTP TLDLEILAFL GLITGVDATS PANSISLGKH HQTLVTSLLS LLLKLGLHRT
LRSHILSFTV QQKATATSLS SAVSLALAPI FTFKVSSPFL SKSAKAPLGA SLKDAIALAD
EPEQKHSSAL HRKAVHSFAV DIMTIPALRK RLPLNLITEL AKHLPFSDLV DWLSSFYPDH
IGTPYPQAHP ALAASSQPTE AAQALSQPYL LANLLAFGSQ RVSFFHDGPS LAKYLQALTN
AQDWLPRSAF EPPTSSSTNK VNGTARKAPP PDAAETYERL RILVSDKHLA AILAISNRFP
TSTRESLFAF ICSAVSAWPL DMRDHVLNRL LYSGAESQGA QNSEQPRSLG PAGTGLIRDF
WRGYVRGSPL ARSLASAHDN TRAREILSSL SDPNTSKEWP ALILVLEMLS KVLLTLGDDE
FLPSGDDSFG VSDGGGARSN ARWLSRDEIL SISALLRNVA FAMYWYEGKA PLINLDGGDV
DDPKGRARTP RVPGMRMTLL SLRTLMTTLL KQLHSRDSRH RFAPADHWLM LRAQQGARSR
HLSALNLAFL SPRLGILNNV PFMIPFDVRV QIFRQFVQID AVENGIYEGR YQRRRAVQIR
RGHVAQDGFA RLAPLGANLK KPLEIVFIDQ FGRPEAGIDG GGLFKEFLTS LVREAFDTNR
GLWKATDAQE LYPNPHTYAT SGEQLEWYEF LGRVIGKALY EGILVDAKFA GFFLSKMLGK
QSFLDDLGSI DTLDKELYKG LISLKNYQGN VEDLSLNFTV TDEEFGVSMT CELIPGGANI
PVTNLNRMEY IYRISHYRLS TQIQHQCNAF FNGLADMINP RWLRNFNREE LSVLISGTDD
PVDLEDLRKH TVLGGYHEQD LTVQHFWKVL EGFDQPMRKA FLKFVTSSPN PPLLGFGQLN
PLFAIRKAGD DKSRLPTAST CVNLLKLPDY EDEQTCRDKL KYAIQSEAGF HLS
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