ID   A0A0F7ZVY4_9HYPO        Unreviewed;       836 AA.
AC   A0A0F7ZVY4;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN   ORFNames=HIM_12582 {ECO:0000313|EMBL:KJZ68027.1};
OS   Hirsutella minnesotensis 3608.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Hirsutella.
OX   NCBI_TaxID=1043627 {ECO:0000313|EMBL:KJZ68027.1, ECO:0000313|Proteomes:UP000054481};
RN   [1] {ECO:0000313|EMBL:KJZ68027.1, ECO:0000313|Proteomes:UP000054481}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3608 {ECO:0000313|EMBL:KJZ68027.1,
RC   ECO:0000313|Proteomes:UP000054481};
RX   PubMed=25359922; DOI=10.1093/gbe/evu241;
RA   Lai Y., Liu K., Zhang X., Zhang X., Li K., Wang N., Shu C., Wu Y., Wang C.,
RA   Bushley K.E., Xiang M., Liu X.;
RT   "Comparative genomics and transcriptomics analyses reveal divergent
RT   lifestyle features of nematode endoparasitic fungus Hirsutella
RT   minnesotensis.";
RL   Genome Biol. Evol. 6:3077-3093(2014).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|RuleBase:RU363044}.
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DR   EMBL; KQ031071; KJZ68027.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F7ZVY4; -.
DR   OrthoDB; 2472492at2759; -.
DR   Proteomes; UP000054481; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR010285; DNA_helicase_pif1-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47642; ATP-DEPENDENT DNA HELICASE; 1.
DR   PANTHER; PTHR47642:SF5; ATP-DEPENDENT DNA HELICASE; 1.
DR   Pfam; PF05970; PIF1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU363044};
KW   DNA damage {ECO:0000256|RuleBase:RU363044};
KW   DNA recombination {ECO:0000256|RuleBase:RU363044};
KW   DNA repair {ECO:0000256|RuleBase:RU363044};
KW   Helicase {ECO:0000256|RuleBase:RU363044};
KW   Hydrolase {ECO:0000256|RuleBase:RU363044};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054481}.
SQ   SEQUENCE   836 AA;  93909 MW;  1F3A169D1DB86618 CRC64;
     MSLVTLARNR GRGEDESHIS LEGPSPGCRE WFQKLRRPHE YAVPIFQGFI SDDHRDEHLV
     YFRRNSVLHL ALFVPWERFL PTTQGDITDI WLRHEASLCR RLRFHVSNIS LLSKSAEDAR
     KDAKLWASRS EGDDTVDIDF PLDEDDDDEE RATVAEHHQN FAALLHTLYN AVRDSHATRG
     SPVLANFIRD LREETLASED KPFMQCSEGF YQQIRRAQDA PLCHTRTLSV EDVQAAAKAQ
     ELLHLRMLDE IETGPQGSPH HAPNADIDDV LARHYDAELP LPHRSQGTAM HGPRMLVNVN
     MATSFTELGH LAASEYTLNP LQTRALQLVC RFLDTYSADP DSASQHLQYT GGPGGTGKSR
     VVEALKWVFS ARGQPHLLQI TGTSGSAAAQ IGGTTLHSAC GLDTRRSADK RIPLFSEAKK
     WVWKQKLVLV IDEVSMLGGA TLYEASCRLQ SLRDCPDRPF GGIPVVLLMG DFYQFAPVRE
     TSLLVDRMAD PLSARLNQAT ISHHRGFRLW LMFKTVVLLE EQVRARDDPE LGALLDRVRH
     GTQTWQDLDL LNTKLIDRSH ITFSNGLRAI TPLNRNRWSL NMEAVVDWAR FNERHISVFV
     STHTWRRAGQ SQYEIAQAVE QGDDSKCKIP GIFFYAQGMP AVVNKNLYTG LKVVNGAEFT
     AADIIPDPKH PGYRLADDVT IRFGPPLGIL LQSSDTASLA VPVLPAEMVL VRPISHILEP
     TDCRFRFLST KCTRRGLPVV PAFVLTDYKS QSKTFADVLL ELRGNRVTNG EPSKCDFTSL
     YVQLSRGTTL RGIKLLSPVR PQDFIGNKLD QKMVDAMQRL KNLASETKRV YEGQGL
//