ID A0A0F8A1U5_9HYPO Unreviewed; 826 AA.
AC A0A0F8A1U5;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN ORFNames=HIM_10888 {ECO:0000313|EMBL:KJZ69719.1};
OS Hirsutella minnesotensis 3608.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Hirsutella.
OX NCBI_TaxID=1043627 {ECO:0000313|EMBL:KJZ69719.1, ECO:0000313|Proteomes:UP000054481};
RN [1] {ECO:0000313|EMBL:KJZ69719.1, ECO:0000313|Proteomes:UP000054481}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3608 {ECO:0000313|EMBL:KJZ69719.1,
RC ECO:0000313|Proteomes:UP000054481};
RX PubMed=25359922; DOI=10.1093/gbe/evu241;
RA Lai Y., Liu K., Zhang X., Zhang X., Li K., Wang N., Shu C., Wu Y., Wang C.,
RA Bushley K.E., Xiang M., Liu X.;
RT "Comparative genomics and transcriptomics analyses reveal divergent
RT lifestyle features of nematode endoparasitic fungus Hirsutella
RT minnesotensis.";
RL Genome Biol. Evol. 6:3077-3093(2014).
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DR EMBL; KQ030684; KJZ69719.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F8A1U5; -.
DR OrthoDB; 2623044at2759; -.
DR Proteomes; UP000054481; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR33481; REVERSE TRANSCRIPTASE; 1.
DR PANTHER; PTHR33481:SF1; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14529; Exo_endo_phos_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000054481}.
FT DOMAIN 680..826
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT COILED 44..71
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 826 AA; 93265 MW; 35E1BF372FAF6B9A CRC64;
MLAKMGSEMV DLKHRVSEQS DTIRKLSATV YKQSTIIQGQ EDLTRGLEVQ VQESKEELRR
KNDEQHKESR QVYQDIQKED MNVKGNLSRL TQKLDTSGEV TVPKLGGPRA TFADVARSLP
ASPPTSIRSI RQAIEEEMRA KNRQETWRCA AVVRESRNAD RVKIICRDEA ELQLVKEAAQ
KTAVDGSRVM RDQLYPVRVD NANRTAILDA EGNTLPGAIE ALSVENRVTI GKISWLSKRE
SGKAYGSMVV GRVGHHSCVR TKTGTDPMFQ LPGNRSQSVF MQEAADMRQM RKSESDERRG
PEGFAALAIS EPHARKIDGR VVTSPMGHHN WTKMIPTCVR DGLWPIRSMP WIRSDLEAEQ
VPVSSADITA AVLRLEEREV MVMSVYVEGK NDEALMSAME VLRDVIDRFR NGTGSCTDVL
LAGDFNRHDL LWSGNEVSAR RQGEGQPIID LMSDFGLCSL LPRGTKTWQG RDKESTIDLV
LASAELADEV TSCVIHPTEH GSDHRAIQTT FDIRVPERTF PQRLLLRNAP WTAIAARVED
ELRPLPWTVG VQTQADQLMR VVTKVLQDLT PRAQPPPYAK RWWTKDLTRL RRMYTYEGKG
EQAEELLSTF FPPLPSRIEP EGERPQRGEI AMPDLTLQEI EEKVMAAKPW KAPGEDGLPA
IVWKKLWHVV KVRVWTLFDS SLREGVVPHQ WRTAKIIPLR KPGKGDYTLA KAWRPISLLS
TLGKILEAVV ADRISYAVEA HVLLPANHFG ARKRRSADQA LVLLQERIYK AWRMGRVLSL
ISFDVKGAYN GVCKERLLDR MRARGIPDRL VVWMDAFCSE RTASVV
//
