ID A0A0F8AT19_LARCR Unreviewed; 429 AA.
AC A0A0F8AT19;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=5-hydroxytryptamine receptor 1A-alpha {ECO:0000313|EMBL:KAE8292041.1};
GN ORFNames=D5F01_LYC09405 {ECO:0000313|EMBL:KAE8292041.1};
OS Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Sciaenidae; Larimichthys.
OX NCBI_TaxID=215358 {ECO:0000313|EMBL:KAE8292041.1, ECO:0000313|Proteomes:UP000424527};
RN [1] {ECO:0000313|EMBL:KAE8292041.1, ECO:0000313|Proteomes:UP000424527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JMULYC20181020 {ECO:0000313|EMBL:KAE8292041.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAE8292041.1};
RA Xiao S.;
RT "Chromosome genome assembly for large yellow croaker.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAE8292041.1}.
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DR EMBL; REGW02000009; KAE8292041.1; -; Genomic_DNA.
DR RefSeq; XP_010731295.1; XM_010732993.2.
DR AlphaFoldDB; A0A0F8AT19; -.
DR GeneID; 104920661; -.
DR KEGG; lco:104920661; -.
DR CTD; 100001828; -.
DR eggNOG; KOG3656; Eukaryota.
DR OrthoDB; 2999405at2759; -.
DR Proteomes; UP000424527; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004993; F:G protein-coupled serotonin receptor activity; IEA:InterPro.
DR GO; GO:0071875; P:adrenergic receptor signaling pathway; IEA:UniProt.
DR GO; GO:0050795; P:regulation of behavior; IEA:InterPro.
DR GO; GO:0046883; P:regulation of hormone secretion; IEA:InterPro.
DR GO; GO:0019229; P:regulation of vasoconstriction; IEA:InterPro.
DR CDD; cd15330; 7tmA_5-HT1A_vertebrates; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000610; 5HT1A_rcpt.
DR InterPro; IPR002231; 5HT_rcpt.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24248; ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR24248:SF191; G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00512; 5HT1ARECEPTR.
DR PRINTS; PR01101; 5HTRECEPTOR.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|RuleBase:RU000688, ECO:0000313|EMBL:KAE8292041.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000424527};
KW Transducer {ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 66..407
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 429 AA; 47474 MW; 0602E65F3851A6E4 CRC64;
MDFITIRSNY SNATSGYPDG VDVVADWDEG ENGTGSGSGS LPDVKLSYQI ITSLLLGALI
LCSIFGNACV VAAIALERSL QNVANYLIGS LAVTDLMVSV LVLPMAALYQ VLNKWTLGQE
ICDVFISLDV LCCTSSILHL CAIALDRYWA ITDPIDYVNK RTPRRAAILI SVTWLIGFSI
SIPPMLGWRS AEDRANPDAC NISQDPGYTI YSTFGAFYIP LILMLVLYGR IFKAARFRIR
KTVKKTETAK VSDKCLTVSP AIFHKKTNGE VVCKGWKRSD ESKPSSPCVN GAVKHGEEGE
SLEIIEVISN SKTHLPLPNT PQSSSHGYEN MNEKNSGAKR KIALARERKT VKTLGIIMGT
FIFCWLPFFI VALVLPFCAE SCYMPDWLAA VINWLGYSNS LLNPIIYAYF NKDFQSAFKK
IIRCKFHRP
//
