ID A0A0F8B2B3_CERFI Unreviewed; 1339 AA.
AC A0A0F8B2B3;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Rho1 guanine nucleotide exchange factor 1 {ECO:0000313|EMBL:KKF95501.1};
GN Name=rgf1 {ECO:0000313|EMBL:KKF95501.1};
GN ORFNames=CFO_g2147 {ECO:0000313|EMBL:KKF95501.1};
OS Ceratocystis fimbriata f. sp. platani.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Ceratocystidaceae; Ceratocystis.
OX NCBI_TaxID=88771 {ECO:0000313|EMBL:KKF95501.1, ECO:0000313|Proteomes:UP000034841};
RN [1] {ECO:0000313|EMBL:KKF95501.1, ECO:0000313|Proteomes:UP000034841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFO {ECO:0000313|EMBL:KKF95501.1,
RC ECO:0000313|Proteomes:UP000034841};
RA Belbahri L.;
RT "Genome sequence of Ceratocystis platani, a major pathogen of plane
RT trees.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKF95501.1}.
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DR EMBL; LBBL01000092; KKF95501.1; -; Genomic_DNA.
DR Proteomes; UP000034841; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd04435; DEP_fRom2; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041675; PH_5.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46572; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46572:SF2; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR Pfam; PF00780; CNH; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF15405; PH_5; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00036; CNH; 1.
DR SMART; SM00049; DEP; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50219; CNH; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000034841}.
FT DOMAIN 610..801
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 985..1278
FT /note="CNH"
FT /evidence="ECO:0000259|PROSITE:PS50219"
FT REGION 1..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1307..1339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..74
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..130
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..244
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1339 AA; 151327 MW; 3883E83A0AFD43CA CRC64;
MSEYRPHDRG HQPPGRAPPQ QQYQQRDAAF SNIFGAAPPP GRSHTMSSSV PPPNFGPADF
HDPRRVPPPP IPQQYQQQQQ QQQQQQQPQQ QSHQHHHQQQ QQQQGHAPQQ RPPNPPYPHR
DQPPAHGQQH PPHPQQQQRA ASAGYHVPNP LAQYQQARRP VGPPPQGGYQ QMGHPQQQRA
DPHAMPPSQL GNSRTPAQRF YQGGGLAPAM NHDQYRTQSL ASTARPQMYQ QTPYGHQQSG
PQHPQQPHQR PPQLQPAGYQ HDGPQFQPFN ANAAAQARTT AHGRVVPERN DERAMSMTGA
YYPADRDSHQ TMSGRVIPNR RPADAQPPQN YPSNGYNPPR SSYGKPSQPS HGSSNSGGGY
SAPGTATRTA SMASSVGDAS ARTFSMASSI APTIVGSEHD SQVAYRPSTG KQTSENGERP
QTAKVRPPIV YPALLSRVAD CLRRRIITSE RMKNGLSYKD AFSGADAVDV LSYIIRTTDR
NLALLLGRAL DAQKFFHDVT YEHRLRDSSN EMYQFKEVEG EEKSSVNGVF VLLSECYSPT
CTRDQLCYSI ACPRRLEQVS RLNLKIRPGL KKEQDNAVVE DDVDQTDEQK LWINSVPQEV
VDSVGDRERK RQEIISELCY TERDFVKDLE YLRDFWIIPL RSRGSPIPAE RRDAVVSNIF
SNAIDHPSIH GVSSRFAKAL TERQQKNPVV SNVGDIFLEF VPQFEPFIIY GSKQMEAKYY
FEGEKSANAN FCKFVDEIER RKESRKLELN GYLTKPTTRL ARYPLLLENV IKYTEDGNKD
KEDLPKVLTY IRDLLSRVNA ESGKAENRFN LRRLDEQLKF RPNERVDLRL REEGRELVFK
CQLKKSPTDP SDINAFLFDH AVLLVKIKQV GKIEEYKAYR RPIPLELLSI REMEEVIPEN
NGTVKRSSSS ILPALRNESG GKKGEGWPIT FRHLGKNGYE LQLFASNQAA RKKWLEFIDT
SQVRLRGRAD FFTETIISYN FFGVGNHVNC VTPFDGGRKL IYGTDNGIYM SDRKLKDAQP
RRVLEAFSVT QIDVLEEYSM LLVLSNKSLV LYNLSALDPN EQAASRRPRK IQSHCNFFKT
GICMGRHLVC CVKSSALSTT IKVYEPNDAA SKGKKQKGLG KMFSAGQDDL KPFKEFYIPT
ESSSVHFLKS KLCVACARGF EVVDLETLET QSLLDQADTS LDFVSRKEGV RPTHIERLNG
EFLLNYSDFS FFVNKHGWRA RPDWKIDWEG MPTNFALSPP WILAFESNFI ELRNIENGFV
HIVPHKNIRM LHSSSHEILF AYEDERGYDV VDSLDFWKSN RRSELPPGGL GAIQAPPTAS
APAAQGGAPQ VPRLPKLDI
//
