ID A0A0F8BMC3_CERFI Unreviewed; 537 AA.
AC A0A0F8BMC3;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 22-FEB-2023, entry version 31.
DE SubName: Full=Ras guanine nucleotide exchange factor A {ECO:0000313|EMBL:KKF93583.1};
GN Name=gefA_1 {ECO:0000313|EMBL:KKF93583.1};
GN ORFNames=CFO_g4060 {ECO:0000313|EMBL:KKF93583.1};
OS Ceratocystis fimbriata f. sp. platani.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Ceratocystidaceae; Ceratocystis.
OX NCBI_TaxID=88771 {ECO:0000313|EMBL:KKF93583.1, ECO:0000313|Proteomes:UP000034841};
RN [1] {ECO:0000313|EMBL:KKF93583.1, ECO:0000313|Proteomes:UP000034841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFO {ECO:0000313|EMBL:KKF93583.1,
RC ECO:0000313|Proteomes:UP000034841};
RA Belbahri L.;
RT "Genome sequence of Ceratocystis platani, a major pathogen of plane
RT trees.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKF93583.1}.
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DR EMBL; LBBL01000226; KKF93583.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F8BMC3; -.
DR Proteomes; UP000034841; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF348; GUANYL-NUCLEOTIDE EXCHANGE FACTOR RASGEF, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04700)-RELATED; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000034841}.
FT DOMAIN 46..172
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 277..517
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 537 AA; 60937 MW; 9ABB36E86AF7AD34 CRC64;
MDESDGEPSS SRRGSDDVPI LQRDGDALYD MELDRSSAKG DHPSNTRNQA AGVTLDDLIN
RLLALRMAKA EHNFANVFLC MYRKFAAPGD LFARILTRLD HVRDDKTQHY LTKTATQLRI
VDVVVRWVSL YPGDFARPAT RRNLREFVRN LATEPIFAIA AQQIQTCLAS SVVDDDDTGW
EMSDDPTEDD ADRAAAGQSV SDMFSGIIAL RLEDDDRMPL THGLDLEIHG HSSLSATSGI
QCHYNSVEDY ERAASKLVPV EMFPMNKARF HQFMEISNEE VVSEMTRIDW IMFSSIRVRD
LVRYVSLSAE QKAKAKSLKN VNRMIMHFNH IARWVANMIL LRDKPKHRAQ IFEKFIDIAH
RLRGYNNYNG LAAVLAGLNS TSIHRLAQTK ALLPADAQKQ LAMLTLLMAT QKSYFAYRLA
WENSPLPRIP FIPLHLRDLV SAEEGNSTLV SSDKNTTLIN WAKFDVLGEV LLPIMRSQGM
EYSNLRRNES VRELLLECRM PTDEDEIYAR STELESTLAN SSLPPDSLKK KFPWFAK
//
