ID A0A0F8BSR9_CERFI Unreviewed; 347 AA.
AC A0A0F8BSR9;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Glycerate dehydrogenase {ECO:0000313|EMBL:KKF95608.1};
DE EC=1.1.1.29 {ECO:0000313|EMBL:KKF95608.1};
GN Name=hprA_1 {ECO:0000313|EMBL:KKF95608.1};
GN ORFNames=CFO_g2043 {ECO:0000313|EMBL:KKF95608.1};
OS Ceratocystis fimbriata f. sp. platani.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Ceratocystidaceae; Ceratocystis.
OX NCBI_TaxID=88771 {ECO:0000313|EMBL:KKF95608.1, ECO:0000313|Proteomes:UP000034841};
RN [1] {ECO:0000313|EMBL:KKF95608.1, ECO:0000313|Proteomes:UP000034841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFO {ECO:0000313|EMBL:KKF95608.1,
RC ECO:0000313|Proteomes:UP000034841};
RA Belbahri L.;
RT "Genome sequence of Ceratocystis platani, a major pathogen of plane
RT trees.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKF95608.1}.
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DR EMBL; LBBL01000086; KKF95608.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F8BSR9; -.
DR Proteomes; UP000034841; Unassembled WGS sequence.
DR GO; GO:0008465; F:glycerate dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43761:SF1; 2-HACID_DH DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR43761; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630); 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719,
KW ECO:0000313|EMBL:KKF95608.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000034841}.
FT DOMAIN 30..320
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 112..281
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 347 AA; 37464 MW; 25EDEAFFE97BBCE0 CRC64;
MSTSPPPKKH HIVVLELVNS PSLSFDFPHT IEYYEVSTND QIGDRIKDAT IVIASTTPIT
AAHLAQAPKL ECIAITATGI EFVDRALFAK AGITVTNCPQ SNVDAVGEHF LALYFACRRK
VVRVHDEVTG ENRTWVKKGL LMSLWEQGPP LSCAQETLGI IGYGALGKKI ETLARGVGFN
KILIADRKDA STARSGRTLF RDVIASATTI VVCCPKSPDT IGLVSSHEFS EMRPEALVLN
LARGGIVCEK ALANALTSGR IFGAGVDVLE KEPAGRGTSP LIPDPEKGEE PIPNLTISGH
VAWYSAQTLV NLRRMLEVGV QAHVKGDMLE NPESKATAVV YRGEIFR
//
