ID A0A0F8CBD1_LARCR Unreviewed; 882 AA.
AC A0A0F8CBD1;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Protein-cysteine N-palmitoyltransferase porcupine {ECO:0000313|EMBL:KKF28809.1};
GN ORFNames=EH28_04828 {ECO:0000313|EMBL:KKF28809.1};
OS Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Sciaenidae; Larimichthys.
OX NCBI_TaxID=215358 {ECO:0000313|EMBL:KKF28809.1};
RN [1] {ECO:0000313|EMBL:KKF28809.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SSNF {ECO:0000313|EMBL:KKF28809.1};
RC TISSUE=Blood {ECO:0000313|EMBL:KKF28809.1};
RX PubMed=25835551;
RA Ao J., Mu Y., Xiang L.X., Fan D., Feng M., Zhang S., Shi Q., Zhu L.Y.,
RA Li T., Ding Y., Nie L., Li Q., Dong W.R., Jiang L., Sun B., Zhang X.,
RA Li M., Zhang H.Q., Xie S., Zhu Y., Jiang X., Wang X., Mu P., Chen W.,
RA Yue Z., Wang Z., Wang J., Shao J.Z., Chen X.;
RT "Genome Sequencing of the Perciform Fish Larimichthys crocea Provides
RT Insights into Molecular and Genetic Mechanisms of Stress Adaptation.";
RL PLoS Genet. 11:E1005118-E1005118(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KQ041264; KKF28809.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F8CBD1; -.
DR eggNOG; KOG2641; Eukaryota.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR InterPro; IPR004299; MBOAT_fam.
DR InterPro; IPR005178; Ostalpha/TMEM184C.
DR PANTHER; PTHR13906; PORCUPINE; 1.
DR PANTHER; PTHR13906:SF23; ZGC:55392; 1.
DR Pfam; PF03062; MBOAT; 1.
DR Pfam; PF03619; Solute_trans_a; 1.
DR SMART; SM01417; Solute_trans_a; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KKF28809.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 99..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 496..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..553
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 565..584
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 623..644
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 664..684
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 696..717
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 740..757
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 835..859
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 882 AA; 98613 MW; 445C4D7AD3B07247 CRC64;
MTPRAAFWKK PTSSGGGTPS QLETSADRMD WSSRLAVWQQ LAESCGLSTI EQGLQQIWGL
LLLCLICRLC FRLGVASTVK HVVSVLAGMY GLFLFFDFHM LWVLFLGALC YLVLLLCRHS
SSRGLFLSFV ILIYLLTGEL HLVDMVTWHK IRGSQMVVAM KAISLAFDMD RGTVGALPSP
AEFLGYVLFV GTVVFGPWIS FSSYKNATEG TKLSWLWLYS SSITLVKSQI CLLVSTCIAP
YIFTLFIPIH GTAVTEKWLL AYETAVSFHF SNFFVGYLSE GTTKMAGAGF TEEKDNIRWD
MSVVKPLAVE MPRSMVLVVT SWNIPMSRWL KTYVFKNAMK LGTFPAILMT YTASALLHGL
SFHLGAVLLS LGFITYVEHV LRKKLASIFS ACILSRPCSS DCSHQHKKEY WVMLLNLVFS
LLAIFHLTYL GSMFDAGADE QEIEEGYAAI HTIHRWWWTE CRVIFLCRMG RGANCSWIGP
EIPLSSEIFS AIKDELWLFL IPAGLAAILL GLFLEEVGFF LRHISSSRRK RLYLWILGMY
PVFGLTSLIA LYVPRSSSLC NFIASLYHSM TLLKFMGLIT DFFGGKARML AALSGQRVSP
NPFPCCCCCC LPMVAINSSS RGWMMAAVLQ LSVVRSILFF VTLILWTDEQ YDYGDVDSVN
PNLYVNGIIC VSTFVSFYGH LLFYKATKSA LHGYGLRAKF ICIIVVLVLC GLQSGILETM
GALEVIPCTP PFSVLARSQL IYHYCVIVEM FCIGLYARHT FRKVEPSVVE EVEVPVGVWQ
VEKSVQTDAV EMTHHKLGPL SEEARPGRRL ISASNPSYSE ENLCRIEHAP LDGFPFPQAR
GQQSGRTEPV KPSSAVEPEE DLTHITVRAD INYQGCKDVT VV
//
