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Database: UniProt
Entry: A0A0F8CK31_LARCR
LinkDB: A0A0F8CK31_LARCR
Original site: A0A0F8CK31_LARCR 
ID   A0A0F8CK31_LARCR        Unreviewed;      1517 AA.
AC   A0A0F8CK31;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   31-JUL-2019, entry version 21.
DE   SubName: Full=Rho GTPase-activating protein 35 {ECO:0000313|EMBL:KKF21626.1};
GN   ORFNames=EH28_01687 {ECO:0000313|EMBL:KKF21626.1};
OS   Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Sciaenidae; Larimichthys.
OX   NCBI_TaxID=215358 {ECO:0000313|EMBL:KKF21626.1};
RN   [1] {ECO:0000313|EMBL:KKF21626.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SSNF {ECO:0000313|EMBL:KKF21626.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:KKF21626.1};
RX   PubMed=25835551;
RA   Ao J., Mu Y., Xiang L.X., Fan D., Feng M., Zhang S., Shi Q., Zhu L.Y.,
RA   Li T., Ding Y., Nie L., Li Q., Dong W.R., Jiang L., Sun B., Zhang X.,
RA   Li M., Zhang H.Q., Xie S., Zhu Y., Jiang X., Wang X., Mu P., Chen W.,
RA   Yue Z., Wang Z., Wang J., Shao J.Z., Chen X.;
RT   "Genome Sequencing of the Perciform Fish Larimichthys crocea Provides
RT   Insights into Molecular and Genetic Mechanisms of Stress Adaptation.";
RL   PLoS Genet. 11:E1005118-E1005118(2015).
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DR   EMBL; KQ041855; KKF21626.1; -; Genomic_DNA.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.10.440; -; 2.
DR   Gene3D; 1.10.555.10; -; 1.
DR   InterPro; IPR002713; FF_domain.
DR   InterPro; IPR036517; FF_domain_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039007; pG1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR032835; RhoGAP-FF1.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   InterPro; IPR039006; RhoGAP_pG2.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF01846; FF; 1.
DR   Pfam; PF00071; Ras; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   Pfam; PF16512; RhoGAP-FF1; 1.
DR   SMART; SM00441; FF; 4.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; SSF48350; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF81698; SSF81698; 1.
DR   PROSITE; PS51676; FF; 3.
DR   PROSITE; PS51852; PG1; 1.
DR   PROSITE; PS51853; PG2; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN      270    327       FF. {ECO:0000259|PROSITE:PS51676}.
FT   DOMAIN      429    483       FF. {ECO:0000259|PROSITE:PS51676}.
FT   DOMAIN      485    550       FF. {ECO:0000259|PROSITE:PS51676}.
FT   DOMAIN      592    774       PG1 pseudoGTPase. {ECO:0000259|PROSITE:
FT                                PS51852}.
FT   DOMAIN      800    970       PG2 pseudoGTPase. {ECO:0000259|PROSITE:
FT                                PS51853}.
FT   DOMAIN     1267   1454       Rho-GAP. {ECO:0000259|PROSITE:PS50238}.
FT   REGION      770    790       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1057   1172       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1198   1260       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1466   1517       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED      413    440       {ECO:0000256|SAM:Coils}.
FT   COILED      478    498       {ECO:0000256|SAM:Coils}.
FT   COILED      916    936       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS   1077   1091       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1126   1161       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1221   1238       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS   1239   1253       Basic. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1466   1483       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1484   1509       Pro-rich. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   1517 AA;  171214 MW;  B3C44AF856081021 CRC64;
     MMMAKKQDVR TPTYNLVVVG LSGTEKEKGQ CGVGKSCLCN RFVRPSADDF YLDHTSVLST
     SDFGGRVVNN DHFLFWGEAG RTMEEGPECR MNVVEQTEFI DDQTFQPHRS TALQPYIKRA
     ASTKLASAEK LMYFCTDQLG LEQDFEQKQM PEGKLMVDGF LLCVDVSRGM NRSFEDQMKF
     VTNLYNQLAK TKKPVVLVLT KCDEGVERYI KDSHTFALAK KNLQVVETSA RSNVNVDLAF
     LTLVQLIDKS RGKPKIIPYF EALKQQSQQI ALAKDRYEWL VNRIVNNHNE TWPAVSRRMQ
     TAPEYKDYVF LEGTAKAKKL FQQHVHRLKQ EHIEKRRKAY LSTLPQALSV LIPELDEIDH
     LSWSGVQKVL ETKRDFTQWF VVLDDTPWET TPHIDIMEDD RIPQDLLETP PAESIYETHL
     EQLRNERKRA EMRWEFKEKL SVSPFITPGK PWEEARSFIM NEDFYQWLDE AEYLDIYNKH
     QKEIIDRAKE DFQELLLEYS ELFYELEVDA KPSKEKMGAI QEVLGEEQRF KALQKLQAER
     DALVLKHIHF VYHPTKDTCP NSPHCVDSKI EQILASRFPT RYPSSDSSRL DGGRAERINL
     VILGKDGLAR EMANEIRALC TSDDRYVLDG RLYELALRPI EGNVRLPVNS FHTPTFTPHG
     CLCLYNSKES LSYVVESIEK LRESTISRRE RENSLAQLPL SLLLVTKRGV GSIGDIGGET
     AQTLIQQGQQ VAGKLQCAYL DPASPGMGYG RNVNEKQINQ MLKGLLESRR SIGSSSPPLP
     PPSSAFRDSQ SQPMLEADLR IVMCLMCGDT YDLDQLLAPF LLPQHCRPAS SLSSGTSVLL
     DFSIGSQRQN IELSLLSFHS SFSLRKTRLV HGYIAVYSAR RKASMETLCA FLCEVQDIIP
     VQLLAVGESQ MELSDSESAK EQVNQGEELA HEIEARFNTV ICGHGGVVGG LHKIDLFQPF
     LKEVVEKRTI VEATHMYDNV AEACTNESIS PRCGSPSPVN ILMDSEDDID PSPPYPTLRE
     DGGLGTHMGS FKLPDLDSSD TFSVLSELST FESKLNNKVP PQVKPKPVRK VNLGPYMDQQ
     GGTNRRSLPQ AVSWAPGSDG GYDPSDYAEP MDAVSKPRPT EEENIYSVPH DSTQGKIITI
     RNANKGHSNG SPGGNGSDSE ADSSSLERRR KLSAIGVKPK LYRDRSKRLG KFSSFRTSFS
     IGSDDEMGGP PKASQDEGGA QKDNSIEESE DPKRRNILKS LRRNTKKPRS KPRHSISKPI
     ESNYFGMPLA TVVTLERPIP VFIEKCIRFI ETTGLSTEGI YRVSGNKAEM ESMQRQFDQD
     HNLDLVEKDF TINTVAGAMK AFFSELPEPL VPYSMQGELV EAFKINDREQ RFQTMKDILR
     RFPKENYEVF KYVISHLNKV SQNNKLNLMT SENLSICFWP TLMRPDFTTM DALTATRTYQ
     TIIESFIHQC SYFFYNQPLA DGLPGSPTST LSSMGGTSAY SCMSPPHSPP PTPQSPIPAL
     LPPSLHPHHP PTEQHTL
//
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