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Database: UniProt
Entry: A0A0F8CPD3_LARCR
LinkDB: A0A0F8CPD3_LARCR
Original site: A0A0F8CPD3_LARCR 
ID   A0A0F8CPD3_LARCR        Unreviewed;       373 AA.
AC   A0A0F8CPD3;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   08-MAY-2019, entry version 24.
DE   SubName: Full=ATP-sensitive inward rectifier potassium channel 1 {ECO:0000313|EMBL:KKF24135.1};
GN   ORFNames=EH28_10937 {ECO:0000313|EMBL:KKF24135.1};
OS   Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Sciaenidae; Larimichthys.
OX   NCBI_TaxID=215358 {ECO:0000313|EMBL:KKF24135.1};
RN   [1] {ECO:0000313|EMBL:KKF24135.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SSNF {ECO:0000313|EMBL:KKF24135.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:KKF24135.1};
RX   PubMed=25835551;
RA   Ao J., Mu Y., Xiang L.X., Fan D., Feng M., Zhang S., Shi Q., Zhu L.Y.,
RA   Li T., Ding Y., Nie L., Li Q., Dong W.R., Jiang L., Sun B., Zhang X.,
RA   Li M., Zhang H.Q., Xie S., Zhu Y., Jiang X., Wang X., Mu P., Chen W.,
RA   Yue Z., Wang Z., Wang J., Shao J.Z., Chen X.;
RT   "Genome Sequencing of the Perciform Fish Larimichthys crocea Provides
RT   Insights into Molecular and Genetic Mechanisms of Stress Adaptation.";
RL   PLoS Genet. 11:E1005118-E1005118(2015).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; KQ041648; KKF24135.1; -; Genomic_DNA.
DR   RefSeq; XP_010755416.1; XM_010757114.2.
DR   STRING; 215358.XP_010755416.1; -.
DR   GeneID; 104940496; -.
DR   KEGG; lco:104940496; -.
DR   CTD; 3758; -.
DR   KO; K04995; -.
DR   OrthoDB; 956263at2759; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003268; K_chnl_inward-rec_Kir1.1.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF6; PTHR11767:SF6; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|EMBL:KKF24135.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     60     83       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    137    160       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       24    166       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      173    341       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   SITE        152    152       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   373 AA;  42326 MW;  459D1DF44327482E CRC64;
     MFGSLSKRFQ DYLVERRSRR TRLVTKDGRC NIEFGNIKYS NHFAFLADFW TTFVEIRWRF
     VLFLFIAAFT LSWFIFGLLW YWIARSNGDL TWQNPESDHT PCVDNVVGLT TAFLYSLETQ
     TTIGYGGRAI TPLCPGAVAL IIIQSLLGAI INCFMCGVIL SKISLPKKRA KTITFSDMAV
     ISPKNGSLCL SIRVANLRKT LMIGSQIYGK LLRTTNTQDG ETIIMDQVNI DFMMDAGKDN
     LFFVCPLTLY HVIDKSSPFF EMAVDTLHRQ EFELVVFLDG TAESTSSACQ VRTSFIPQEI
     MWGYNFLPII SRSKEGKYRV DFSNFSKAVP VATAHCAYCF HNIKGNHHHS KDGHDNQGFE
     VIDINDPPNV TKM
//
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