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Database: UniProt
Entry: A0A0F8CPM0_LARCR
LinkDB: A0A0F8CPM0_LARCR
Original site: A0A0F8CPM0_LARCR 
ID   A0A0F8CPM0_LARCR        Unreviewed;       763 AA.
AC   A0A0F8CPM0;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   10-APR-2019, entry version 23.
DE   RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415};
GN   ORFNames=EH28_02789 {ECO:0000313|EMBL:KKF24315.1};
OS   Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Sciaenidae; Larimichthys.
OX   NCBI_TaxID=215358 {ECO:0000313|EMBL:KKF24315.1};
RN   [1] {ECO:0000313|EMBL:KKF24315.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SSNF {ECO:0000313|EMBL:KKF24315.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:KKF24315.1};
RX   PubMed=25835551;
RA   Ao J., Mu Y., Xiang L.X., Fan D., Feng M., Zhang S., Shi Q., Zhu L.Y.,
RA   Li T., Ding Y., Nie L., Li Q., Dong W.R., Jiang L., Sun B., Zhang X.,
RA   Li M., Zhang H.Q., Xie S., Zhu Y., Jiang X., Wang X., Mu P., Chen W.,
RA   Yue Z., Wang Z., Wang J., Shao J.Z., Chen X.;
RT   "Genome Sequencing of the Perciform Fish Larimichthys crocea Provides
RT   Insights into Molecular and Genetic Mechanisms of Stress Adaptation.";
RL   PLoS Genet. 11:E1005118-E1005118(2015).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU046415}.
CC       Nucleus {ECO:0000256|RuleBase:RU046415}.
CC   -!- SIMILARITY: Belongs to the transcription factor STAT family.
CC       {ECO:0000256|RuleBase:RU046415}.
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DR   EMBL; KQ041625; KKF24315.1; -; Genomic_DNA.
DR   RefSeq; XP_019120649.1; XM_019265104.1.
DR   RefSeq; XP_019120650.1; XM_019265105.1.
DR   STRING; 215358.XP_010738354.1; -.
DR   GeneID; 104926239; -.
DR   KEGG; lco:104926239; -.
DR   KO; K11220; -.
DR   OrthoDB; 327469at2759; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.532.10; -; 1.
DR   Gene3D; 1.10.8.1200; -; 1.
DR   Gene3D; 2.60.40.630; -; 1.
DR   Gene3D; 3.30.505.10; -; 1.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR001217; STAT.
DR   InterPro; IPR038295; STAT1_C_sf.
DR   InterPro; IPR022752; STAT1_TAZ2-bd_C.
DR   InterPro; IPR036535; STAT_N_sf.
DR   InterPro; IPR013800; STAT_TF_alpha.
DR   InterPro; IPR015988; STAT_TF_coiled-coil.
DR   InterPro; IPR013801; STAT_TF_DNA-bd.
DR   InterPro; IPR012345; STAT_TF_DNA-bd_N.
DR   InterPro; IPR013799; STAT_TF_prot_interaction.
DR   PANTHER; PTHR11801; PTHR11801; 1.
DR   Pfam; PF00017; SH2; 1.
DR   Pfam; PF12162; STAT1_TAZ2bind; 1.
DR   Pfam; PF01017; STAT_alpha; 1.
DR   Pfam; PF02864; STAT_bind; 1.
DR   Pfam; PF02865; STAT_int; 1.
DR   SMART; SM00964; STAT_int; 1.
DR   SUPFAM; SSF47655; SSF47655; 1.
DR   SUPFAM; SSF48092; SSF48092; 1.
DR   SUPFAM; SSF49417; SSF49417; 1.
DR   SUPFAM; SSF55550; SSF55550; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU046415};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|RuleBase:RU046415};
KW   DNA-binding {ECO:0000256|RuleBase:RU046415};
KW   Nucleus {ECO:0000256|RuleBase:RU046415};
KW   Phosphoprotein {ECO:0000256|RuleBase:RU046415};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191,
KW   ECO:0000256|RuleBase:RU046415};
KW   Transcription {ECO:0000256|RuleBase:RU046415};
KW   Transcription regulation {ECO:0000256|RuleBase:RU046415}.
FT   DOMAIN      571    667       SH2. {ECO:0000259|PROSITE:PS50001}.
FT   COILED      137    181       {ECO:0000256|SAM:Coils}.
FT   COILED      264    284       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   763 AA;  87938 MW;  9E4AA92C87D20726 CRC64;
     MAQWCQLQML DCKYLEQVDQ LYDDSFPMDI RQYLSKWIES IDWDTVAIQD SLATVRFHDL
     LAQLDDQHSR FALENNFLLQ HNIRKIKRNL QDRFQEDPVH MAMIISRNLK EEQKILDTAK
     SAEQEGEGTV SAMVVEKQKL DLKVKEMKDR VQVADQNIKN LEDLQDEYDF KVNTLKNREN
     EINGMTQKEL EKEKMTVGRM CFELKAKRQD VVTQLTDLLN VTQALLSDLI SEELPEWKQR
     QQIACIGGPP NACVDQLQNW FTAVAESLQQ VRQHLKKLQE LEQKFSYESD PITQKKAYLE
     ARALDLVKNL LSNSLVVERQ PCMPTHPQRP LVLKTGVQFT VKLRFLVKLQ EFNYQLKVKA
     VFDKDVTEKK GFRKFNILGT NTKVMNMEES NGSLAAEFRH LQLKEQKVAG NRTNEGPLIV
     TEELHSLSFE SELQLNQSGL DIKLEAISLP VVVISNVCQL PSGWASILWY NMLTTEPKNL
     KFFLSPPSAK WSQLSEILSW QFSSVTKRGL NQEQLNMLAD KLLGAKAQRN PEGLIPWTKF
     CKQSANEKAF PFWLWIEGIL DVIKRHLLSL WNDGSIMGFI SKEREKALLS DKCPGTFLLR
     FSESSREGAI TFTWIEHDVH DKPVFHSVEP YTKKELTAVS LPDIIRTYKV MAAENIPENP
     LRFLYPNIPK DKAFGKYYPK PSEAAEPMDV ENPERTGYMK TELISVSEVH PSRLQDNMMP
     MSPDDYKALS QYVSPRDIDA VANNLISGFE FDAEMSAEFP DQN
//
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