ID A0A0F8CUK0_CERFI Unreviewed; 1064 AA.
AC A0A0F8CUK0;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Inhibitory regulator protein BUD2/CLA2 {ECO:0000313|EMBL:KKF94392.1};
GN Name=BUD2 {ECO:0000313|EMBL:KKF94392.1};
GN ORFNames=CFO_g3253 {ECO:0000313|EMBL:KKF94392.1};
OS Ceratocystis fimbriata f. sp. platani.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Ceratocystidaceae; Ceratocystis.
OX NCBI_TaxID=88771 {ECO:0000313|EMBL:KKF94392.1, ECO:0000313|Proteomes:UP000034841};
RN [1] {ECO:0000313|EMBL:KKF94392.1, ECO:0000313|Proteomes:UP000034841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFO {ECO:0000313|EMBL:KKF94392.1,
RC ECO:0000313|Proteomes:UP000034841};
RA Belbahri L.;
RT "Genome sequence of Ceratocystis platani, a major pathogen of plane
RT trees.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKF94392.1}.
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DR EMBL; LBBL01000164; KKF94392.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F8CUK0; -.
DR Proteomes; UP000034841; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR CDD; cd00030; C2; 1.
DR CDD; cd05137; RasGAP_CLA2_BUD2; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194:SF60; GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF00616; RasGAP; 1.
DR SMART; SM00239; C2; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000034841}.
FT DOMAIN 292..442
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 497..731
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 105..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 163..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 859..897
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 916..936
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 970..1064
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1026..1064
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1064 AA; 118005 MW; C0F7B0CFEE1CCE0D CRC64;
MRGDIEYQTE AGGPWYRGVS WIEEDQGCLM FDSGHTKGIV LTLCADLRGS RIVPVLDPEN
GRTCLDLITG FPLMDILIRP CVDEEVDLWI AALLCWQQVS LPPSKHSGGS SAGSNSHNSS
RPELRRRGSS LAQNRNVNSQ GKSPSIIKVA KVHVWDKGFP KSPREIFKSP SPLDSRTTKD
NNKDHSWARV SCLLQDNGEL QLLAENDVSV LTLIDLHQLS RSAIQRMDCT LFDDMEFCLA
IYPMYAPGST HLSIFRPIYM SFESHVFVDV WYVLLRAFAQ PRLFRYNSQS LGPPEPVTDI
ESSTHGEIFR IERTLKVRIV EAKLKDHAGA LEKSGHGHSR HNTGDESVVG NYFAEVLLDG
EIRTRTAIKH NTKNPFWRED CVLADIPPSP PLLSIVLKRI DGLEVEKKIH FSKPCPPSEH
RCGTVDIPID QMQTPDEHEH WLPILNANNQ SIGTMLVKIH HEEMAVLLAS EYESLRELLQ
RFPSGLTSQI ARQIPGGLRR LAEVTLDIFQ VSGKVHEWLM SLVEEEIDGI TNQAPVKNYR
FSSRLRSNES IDFGIDREQL VRDMSKSLAG EANLLFRGNS LLTQALECYM RRLGKGYLEE
VLRDKIVEIN EMNPNCEIDP SKLESGDDIQ RHWALLIKLT TEVWACISQS ANQLPTEMRH
ILKYVRAVAE DRYGDFLRAV SYTSVTGFLF LRFICPAILS PKLFSMLRDL PEPRAQRTFT
LIAKALQAMA NLSTFGQKES WMEPMNKFLN SRRASLKLYV DEVCSIPADQ AIPLLPPSYS
TPLAIMNRLS ATAREGIPVL PHLVDPTRSL ATLVSLWSNA NSSSNSDQPG GDIALFNSTC
QVLHHRAAAC LKNAELLREP TATSDSQSTE DIPSADGEDE LSGVVSSNIP SNRSTSSLAS
LSGMWTLTRT ERSVEHLRAP SSAGSDVLET ASSRRRLNST RDAAADLASG TGFGALGRLD
MQSLAQLQLQ TQAQRGSGWP SSAPPMSPIG TLRGSRNGRT TRNILSGIIR MGRGSETGSQ
AQAEAGEEKD TGKAKAEKES SKVKTEKESS KAKAEKESGK NKAK
//
