ID   A0A0F8D2L1_CERFI        Unreviewed;       770 AA.
AC   A0A0F8D2L1;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   22-FEB-2023, entry version 18.
DE   RecName: Full=MMS19 nucleotide excision repair protein {ECO:0000256|RuleBase:RU367072};
GN   Name=mms19 {ECO:0000313|EMBL:KKF96987.1};
GN   ORFNames=CFO_g642 {ECO:0000313|EMBL:KKF96987.1};
OS   Ceratocystis fimbriata f. sp. platani.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Microascales; Ceratocystidaceae; Ceratocystis.
OX   NCBI_TaxID=88771 {ECO:0000313|EMBL:KKF96987.1, ECO:0000313|Proteomes:UP000034841};
RN   [1] {ECO:0000313|EMBL:KKF96987.1, ECO:0000313|Proteomes:UP000034841}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFO {ECO:0000313|EMBL:KKF96987.1,
RC   ECO:0000313|Proteomes:UP000034841};
RA   Belbahri L.;
RT   "Genome sequence of Ceratocystis platani, a major pathogen of plane
RT   trees.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Key component of the cytosolic iron-sulfur protein assembly
CC       (CIA) complex, a multiprotein complex that mediates the incorporation
CC       of iron-sulfur cluster into apoproteins specifically involved in DNA
CC       metabolism and genomic integrity. In the CIA complex, MMS19 acts as an
CC       adapter between early-acting CIA components and a subset of cellular
CC       target iron-sulfur proteins. {ECO:0000256|RuleBase:RU367072}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU367072}.
CC   -!- SIMILARITY: Belongs to the MET18/MMS19 family.
CC       {ECO:0000256|RuleBase:RU367072}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKF96987.1}.
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DR   EMBL; LBBL01000021; KKF96987.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F8D2L1; -.
DR   Proteomes; UP000034841; Unassembled WGS sequence.
DR   GO; GO:0097361; C:CIA complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0097428; P:protein maturation by iron-sulfur cluster transfer; IEA:UniProtKB-UniRule.
DR   InterPro; IPR039920; MET18/MMS19.
DR   InterPro; IPR024687; MMS19_C.
DR   InterPro; IPR029240; MMS19_N.
DR   PANTHER; PTHR12891; DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19; 1.
DR   PANTHER; PTHR12891:SF0; MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG; 1.
DR   Pfam; PF12460; MMS19_C; 1.
DR   Pfam; PF14500; MMS19_N; 1.
PE   3: Inferred from homology;
KW   DNA damage {ECO:0000256|RuleBase:RU367072};
KW   DNA repair {ECO:0000256|RuleBase:RU367072};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367072};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034841};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          62..278
FT                   /note="MMS19 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14500"
FT   DOMAIN          308..680
FT                   /note="MMS19 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12460"
SQ   SEQUENCE   770 AA;  84109 MW;  6ECC21F8F665DB0B CRC64;
     MADFDQLALK FVLEDDHPTR DALAAEAAEV IKSTPRASNP IRKWVESVRP WILGDDGEAG
     SGDRIARARA LDFLSTTLHL LDKDFLRLDQ IKVLIAYFSS MFTIDHRSGI LPSAKALSTL
     TSMEFFPVDA APSMLHSVCA MGDEFRNQIP VTRLAVYELF TTCVTNPAIA SELRSKQSPD
     LVFIKEMIAM CGSERDPKNI LKWFGLLAIF LREFHPSTEL SLEIFNTFSA YFPISLRASQ
     HPSGITADDL KLALRDCFVA NPLMAPHAFP FLLSKIEQGT AIRLLYLQKP EGLSDEEQLA
     FRAVDPTFVT LYESTLKKMF AERSAINRNA VQSLVNLAAP FNDGSDSSRR FIFFLGQLST
     YVISQLTEKQ QQLLSLQEEV FALFHSDVIK KVIDTVHPAE YFEEKSPDTL LSSPSIVPSC
     LDLSTSCLQA LRPSVVSGLF SSGVGQEVIA QCLLSHDATE PTVARAYWLT VLANKHAFEK
     SPKLLALLES RLAVLVTSSD DVLVTANAVY GLLAGALRRY TGSSLSASLD LLRKLTSNPT
     LGHIFAQWYD YLFSPKPRLA KAFHGLTKPT WTQRAYIELL VPLLQAALPC PTSNPTEKLA
     AANATVAVLA AVRHLSFTVY QDDAPVLVRT VLAALSTLPS SLVAAPALAI LEAVMASSPT
     LLESHARSAI DVCLRISVLD TSTASIAASA DNSWMPSGFG EISNPGPVLA AARKSALALL
     GQMPERFEHR HLVELAPRVK RALAVASGDK VRAVRGIATK ARMAWNTVDA
//