ID A0A0F8D3U0_LARCR Unreviewed; 395 AA.
AC A0A0F8D3U0;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Isotocin receptor {ECO:0000313|EMBL:KAE8298476.1};
GN ORFNames=D5F01_LYC02975 {ECO:0000313|EMBL:KAE8298476.1};
OS Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Sciaenidae; Larimichthys.
OX NCBI_TaxID=215358 {ECO:0000313|EMBL:KAE8298476.1, ECO:0000313|Proteomes:UP000424527};
RN [1] {ECO:0000313|EMBL:KAE8298476.1, ECO:0000313|Proteomes:UP000424527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JMULYC20181020 {ECO:0000313|EMBL:KAE8298476.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAE8298476.1};
RA Xiao S.;
RT "Chromosome genome assembly for large yellow croaker.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|RuleBase:RU046427}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU046427}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC Vasopressin/oxytocin receptor subfamily.
CC {ECO:0000256|RuleBase:RU046427}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU046427}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAE8298476.1}.
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DR EMBL; REGW02000003; KAE8298476.1; -; Genomic_DNA.
DR RefSeq; XP_010731101.1; XM_010732799.2.
DR RefSeq; XP_019116329.1; XM_019260784.1.
DR AlphaFoldDB; A0A0F8D3U0; -.
DR GeneID; 104920519; -.
DR KEGG; lco:104920519; -.
DR CTD; 796298; -.
DR eggNOG; KOG3656; Eukaryota.
DR OrthoDB; 2879183at2759; -.
DR Proteomes; UP000424527; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004990; F:oxytocin receptor activity; IEA:InterPro.
DR GO; GO:0005000; F:vasopressin receptor activity; IEA:InterPro.
DR CDD; cd15387; 7tmA_OT_R; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR002062; Oxytocn_rcpt.
DR InterPro; IPR001817; Vasoprsn_rcpt.
DR PANTHER; PTHR24241; NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR24241:SF89; OXYTOCIN RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00665; OXYTOCINR.
DR PRINTS; PR00896; VASOPRESSINR.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU046427};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180,
KW ECO:0000256|RuleBase:RU046427};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU046427};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU046427};
KW Reference proteome {ECO:0000313|Proteomes:UP000424527};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU046427};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU046427};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU046427}.
FT TRANSMEM 47..68
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 118..139
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 204..232
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 277..298
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 310..333
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT DOMAIN 60..330
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 395 AA; 45196 MW; F4D0B3D2FDF09349 CRC64;
MEDLLREQNS WAQNVSWSNS SRGNDSHLGN TTVNPLKRNE EVAKVEVTVL VLVLLLALTG
NLCVLWAIHA TKHSQSRMYY FMKHLSIADL VVAIFQVLPQ LIWDITFRFY GPDLLCRLVK
YLQVVGMFAS TYMLVLMSID RCLAICQPLR SVHKRKDRYY VIASWMLSLI FSTPQAYIFS
LKEVGDGVYD CWGDFVQPWG AKAYITWMSL SIYIFPVAIL SICYGLICFK IWQNFNLKTK
REHFLALTTR SSKGAHPLSR VSSVRLISKA KIRTVKMTFV VVLAYIVCWT PFFFVQMWSA
WDPAAPREDM AFIIAMLLAS LNSCCNPWIY MFFAGHLFQD LMQCFFCCCR QYMTASSCSS
DQQCRHKSSS STYVIKNTSS QRSLTHTSST GGPGH
//
