ID   A0A0F8UF78_9EURO        Unreviewed;       814 AA.
AC   A0A0F8UF78;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Polynucleotide 5'-hydroxyl-kinase GRC3 {ECO:0000256|ARBA:ARBA00019824};
DE   AltName: Full=Polynucleotide 5'-hydroxyl-kinase grc3 {ECO:0000256|ARBA:ARBA00018706};
GN   ORFNames=ARAM_001622 {ECO:0000313|EMBL:KKK18329.1};
OS   Aspergillus rambellii.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=308745 {ECO:0000313|EMBL:KKK18329.1, ECO:0000313|Proteomes:UP000034291};
RN   [1] {ECO:0000313|EMBL:KKK18329.1, ECO:0000313|Proteomes:UP000034291}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SRRC1468 {ECO:0000313|EMBL:KKK18329.1,
RC   ECO:0000313|Proteomes:UP000034291};
RA   Moore G.G., Beltz S.B., Mack B.M.;
RT   "Draft Genome Sequences of Two Closely-Related Aflatoxigenic Aspergillus
RT   Species Obtained from the Cote d'Ivoire.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Polynucleotide 5'-kinase involved in rRNA processing.
CC       {ECO:0000256|ARBA:ARBA00003798}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
CC       {ECO:0000256|ARBA:ARBA00011003}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKK18329.1}.
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DR   EMBL; JZBS01002519; KKK18329.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0F8UF78; -.
DR   STRING; 308745.A0A0F8UF78; -.
DR   OrthoDB; 5480745at2759; -.
DR   Proteomes; UP000034291; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR045116; Clp1/Grc3.
DR   InterPro; IPR032319; CLP1_P.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12755; CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; 1.
DR   PANTHER; PTHR12755:SF3; POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9; 1.
DR   Pfam; PF16575; CLP1_P; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034291};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          328..530
FT                   /note="Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop"
FT                   /evidence="ECO:0000259|Pfam:PF16575"
FT   REGION          1..122
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        44..113
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   814 AA;  89625 MW;  ADA4B6E581D64CF8 CRC64;
     MKRKAEKQQA AAPVSAFAAR KARQQQAQAQ AVEASVKPAH TESAGEPPSK KPRRSLDDKT
     IAQPIVEERQ TRSQKQKALK TEEVPLKKNE DITRKARDRK PEPVVSSDHE EQGPSDEGSE
     DEDAIVEEAG VMSVSENGDG YESPADTPVQ TVEFPLSKAR LNKNNIVYSD EDTLCVRIRE
     KLSFVLIGQY DLWVKRGVVS LMGAKLHPSP RVYRVYAPST HSLPVLKCVS GVDGAAEVEF
     KSCHSGIYRL RELSPLYQRV WNHKNTPADK LSLQKVGGAS KRTFSVLHTS GDDPLNRHLR
     PLHMEKQWSA AIKSLSQRGG RLQVLICGPK ASGKSTFGRY LLNHLLSPAP QTESQYRNTD
     GVAFLDLDPG QPEFSPMGQI YLAHLRSPVF GPPFTHPALD SRREGTIIRA HHIGATSPKE
     DPDHYVLAAT NLLEHYRALL ASYPQCPLII NYPGWIFGLG LEVATYLVRS LGLSDVVYMS
     EKGPMEVVEP LSQAARAAKT ALTILPSQPT EFVSRSSAQL RSMQMQSYFH LSHPTEIANP
     LWLEGPVSRT KPFLVHYAGP KQGIYGIMGS GSQISLDLLA ESLEGALVAV VAVESPTAIP
     VAGPTPLPNS HHHDDYAGHD EMDMDAKPST TTTTTTTMPT LESNITRTSK EHLPYLFVGA
     GSSTPLDPKS SRSLGLAIVR SIKATSHQLE LITPIPGSQI RGAVEQGHGI VLVRGLLDNP
     NWAISEEYYL AQAAERRFRS RVRPGRHSNP KSTGDLGDEQ VRILGTLQDR IRRAQNVPWM
     TVVEDRRHVV QRGQEGALWK LRKKAYPDSG SEAE
//