ID A0A0F9WCW1_9MICR Unreviewed; 370 AA.
AC A0A0F9WCW1;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Polynucleotide 5'-hydroxyl-kinase GRC3 {ECO:0000256|ARBA:ARBA00019824};
DE AltName: Full=Polynucleotide 5'-hydroxyl-kinase grc3 {ECO:0000256|ARBA:ARBA00018706};
GN ORFNames=AAJ76_2500027613 {ECO:0000313|EMBL:KKO75301.1};
OS Vairimorpha ceranae.
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nosematidae;
OC Vairimorpha.
OX NCBI_TaxID=40302 {ECO:0000313|EMBL:KKO75301.1, ECO:0000313|Proteomes:UP000034350};
RN [1] {ECO:0000313|EMBL:KKO75301.1, ECO:0000313|Proteomes:UP000034350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PA08 1199 {ECO:0000313|EMBL:KKO75301.1,
RC ECO:0000313|Proteomes:UP000034350};
RX PubMed=25914091;
RA Pelin A., Selman M., Aris-Brosou S., Farinelli L., Corradi N.;
RT "Genome analyses suggest the presence of polyploidy and recent human-driven
RT expansions in eight global populations of the honeybee pathogen Nosema
RT ceranae.";
RL Environ. Microbiol. 0:0-0(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKO75301.1}.
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DR EMBL; JPQZ01000025; KKO75301.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F9WCW1; -.
DR VEuPathDB; MicrosporidiaDB:AAJ76_2500027613; -.
DR VEuPathDB; MicrosporidiaDB:G9O61_00g009410; -.
DR VEuPathDB; MicrosporidiaDB:NCER_100118; -.
DR OrthoDB; 56092at2759; -.
DR Proteomes; UP000034350; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; IEA:InterPro.
DR GO; GO:0031124; P:mRNA 3'-end processing; IEA:InterPro.
DR Gene3D; 2.60.120.1030; Clp1, DNA binding domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.330; Pre-mRNA cleavage complex subunit Clp1, C-terminal domain; 1.
DR InterPro; IPR045116; Clp1/Grc3.
DR InterPro; IPR010655; Clp1_C.
DR InterPro; IPR038238; Clp1_C_sf.
DR InterPro; IPR032324; Clp1_N.
DR InterPro; IPR038239; Clp1_N_sf.
DR InterPro; IPR032319; CLP1_P.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12755; CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; 1.
DR PANTHER; PTHR12755:SF6; POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1; 1.
DR Pfam; PF06807; Clp1; 1.
DR Pfam; PF16573; CLP1_N; 1.
DR Pfam; PF16575; CLP1_P; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000034350}.
FT DOMAIN 5..87
FT /note="Clp1 N-terminal beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF16573"
FT DOMAIN 102..232
FT /note="Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop"
FT /evidence="ECO:0000259|Pfam:PF16575"
FT DOMAIN 268..369
FT /note="Pre-mRNA cleavage complex subunit Clp1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF06807"
SQ SEQUENCE 370 AA; 42582 MW; 3BE96B6553D5E820 CRC64;
MELTLLKNQE YRVEVNDTQK FKVMVMSGSA EIKGQELINE KWYTIKNTKT VIFTYTGCKL
KIDGTCDLQF ISNNTNVPDI LKLFTSLINK ECNDKTFMVV GKGRTTFCTT IINYFIRLHK
KVLFTEIDLK KGNIFPGSLS TIHVDTLVEY NEHFKLSNVL SFYYGSTEIK NKDLYTLLLS
RLKEAIDKKK VDDLHLILCP EETSKYYQEI VKMFNVDKLI CVGDERKFHM IDVPINKMFI
PLSGYINDSS VDKSITRYFN GLNNEYTPYS FCVKRKWNVV RVGEECLAPE SALPLGGTRK
LDILEIKDVK LENNCVLGIS DAKTSEEIIK SPVLGYCVVI NQDIFKILCT QTKLPKCSYF
IQGEIKYSDF
//
