ID A0A0F9X9H2_TRIHA Unreviewed; 948 AA.
AC A0A0F9X9H2;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Peptidase {ECO:0000313|EMBL:KKO97422.1};
GN ORFNames=THAR02_10477 {ECO:0000313|EMBL:KKO97422.1};
OS Trichoderma harzianum (Hypocrea lixii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=5544 {ECO:0000313|EMBL:KKO97422.1, ECO:0000313|Proteomes:UP000034112};
RN [1] {ECO:0000313|Proteomes:UP000034112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6776 {ECO:0000313|Proteomes:UP000034112};
RX PubMed=26067977; DOI=10.1128/genomeA.00647-15;
RA Baroncelli R., Piaggeschi G., Fiorini L., Bertolini E., Zapparata A.,
RA Pe M.E., Sarrocco S., Vannacci G.;
RT "Draft whole-genome sequence of the biocontrol agent Trichoderma harzianum
RT T6776.";
RL Genome Announc. 3:E0064715-E0064715(2015).
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240, ECO:0000256|RuleBase:RU003355}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKO97422.1}.
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DR EMBL; JOKZ01000570; KKO97422.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F9X9H2; -.
DR OMA; ELQPDFH; -.
DR OrthoDB; 662485at2759; -.
DR Proteomes; UP000034112; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07489; Peptidases_S8_5; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 2.
DR InterPro; IPR010435; Fn3_5.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034187; Peptidases_S8_5.
DR PANTHER; PTHR43399; SUBTILISIN-RELATED; 1.
DR PANTHER; PTHR43399:SF4; TK-SUBTILISIN; 1.
DR Pfam; PF06280; fn3_5; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000034112};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..948
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002529993"
FT DOMAIN 164..591
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 624..738
FT /note="Fn3-like"
FT /evidence="ECO:0000259|Pfam:PF06280"
FT ACT_SITE 173
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 225
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 551
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 948 AA; 101504 MW; 4533C1056E48C226 CRC64;
MKLNAALGLL ALVGGASSSL TITTNTNKNP LVSNQNTTVV PNTFIVELQP DFHPDLQPKE
RFAKTAPGAK VGYRVRQQYN STDFFYGVSV SFNTHVDLST LRQSTGVKNA WKVATVPRPE
PYHLRGAPKI SQGTSLPNLR GSAKVNQPLA MSNVQKLHDQ GIKGKGVQVA IIDTGVDYRH
PALGGGFGRG HKIALGYDFV GDDYDGSNTP VPDPDPLATC VDGGHGTHTT GIVGMEDPDN
VGFGLVGVAP EATLAAYRVF GCEGGTSNEL IISAMLKAAQ NGADVVSISI GGYDIWEEIN
PFDEVITRLA NHGVAVVAAI GNFGTAGVFS TTAPGISTNA LSVGSIENDV YPTVYTAHDD
KHKAIDYVSV FPATSLGRVE VYQLGAGLDI PIDANVSSGC YEPAWDALAA ASVDWNNTIL
LVSWVSWCGT NWGTAVDLGA QAILVYQPEE LLIVVDEPED PTTLLYLDYS NSQQIVNNLS
QLPAGQKYYL TFDGKKPSSA TDPLGRTPDD FSSFGPTVEM SLAPKVSAPG GTILATWPLE
AGGYAVLSGT SMATPFAAGS LALLKSQQPH LSVAELYARL MTTAGPVNEP NSKKIASTAR
QGGGLIDVYA AVKADTVISP SELSLHDSET PAPRKITITN QSKSRKKYSF QHSPGSFYRV
YYNYLTGNTD YNGGSEVIPL DVPASASFSQ SSLTLGPGQS ATVQVQIKPQ HDDWPWSLPV
YGGFVKIISD DAAYSIPYIG VPYNRTEVGP IMHNVTTQLP YDSPGILKLP ANDLFLADGQ
IPTPNIDSYN WSTDPSKSFI PVFRVDVLLP SRFIRFDLVP ANVSFVPSIY GFDPNVHIDY
EPPSQAILPG FLGVPTYGQL FSITVDDAPS NSPTLSQPVI NHFFAQALVL PTLTNDDNVS
YNISSGDYRP LLRALRWNGN ETNPDDYESW LGPVIRADIP SDEFPTDT
//
