ID A0A0F9XC73_TRIHA Unreviewed; 1098 AA.
AC A0A0F9XC73;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Protein STU1 {ECO:0000313|EMBL:KKP02671.1};
GN ORFNames=THAR02_05214 {ECO:0000313|EMBL:KKP02671.1};
OS Trichoderma harzianum (Hypocrea lixii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=5544 {ECO:0000313|EMBL:KKP02671.1, ECO:0000313|Proteomes:UP000034112};
RN [1] {ECO:0000313|Proteomes:UP000034112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6776 {ECO:0000313|Proteomes:UP000034112};
RX PubMed=26067977; DOI=10.1128/genomeA.00647-15;
RA Baroncelli R., Piaggeschi G., Fiorini L., Bertolini E., Zapparata A.,
RA Pe M.E., Sarrocco S., Vannacci G.;
RT "Draft whole-genome sequence of the biocontrol agent Trichoderma harzianum
RT T6776.";
RL Genome Announc. 3:E0064715-E0064715(2015).
CC -!- FUNCTION: Microtubule binding protein that promotes the stabilization
CC of dynamic microtubules. Required for mitotic spindle formation.
CC {ECO:0000256|ARBA:ARBA00024889}.
CC -!- SUBUNIT: Interacts with microtubules. {ECO:0000256|ARBA:ARBA00011375}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}.
CC -!- SIMILARITY: Belongs to the CLASP family.
CC {ECO:0000256|ARBA:ARBA00009549}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKP02671.1}.
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DR EMBL; JOKZ01000140; KKP02671.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F9XC73; -.
DR OMA; GNAPHDF; -.
DR OrthoDB; 1369289at2759; -.
DR Proteomes; UP000034112; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:UniProt.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024395; CLASP_N_dom.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR21567; CLASP; 1.
DR PANTHER; PTHR21567:SF9; CLIP-ASSOCIATING PROTEIN; 1.
DR Pfam; PF12348; CLASP_N; 2.
DR SMART; SM01349; TOG; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000034112}.
FT DOMAIN 28..257
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 308..542
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 844..1096
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REGION 256..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..796
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 829..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 681..727
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 735..750
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..795
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 832..856
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1098 AA; 120294 MW; 745E7BDDE26C5621 CRC64;
MASTTLCNRK ILTKAQTVQQ QLRSATEFMA DTKLTDDQVN NLTAVLRNDN THFDVKVQYV
NTIKTGIKQH NVPETCIPQL FEGLRSASSS QHVALATAGF TALNHLFTRM SRQEPKYLAK
EAARTLPLVI EKLGDSKDKP RALAMQSLNT LYAVAPADVE RSMRNMAMGS KNPRAKEASM
QWLLETHQQH GLPFRGYVPN LMELLEDADG MVRDMAKNTV IELFKNAPGA AKSDLKRQLK
NFKVRPAIEQ AIVKALAPTG PRSETPSDAA PAPPRPALSA PSSFAVSDRP VTPMEIPAEA
VEPQYVNTHR ELDDIIKEMA PHFEGKESEH NWMKREKGIV TLRRLVAGNG PADFLDTFMP
GLKALLDGII KAVNSLRTSL SKEGCSLVQE MAVAFGPSMD PLVELLMQTF MKLAANTKKI
SSQMANAAIE AIVSKVTYTP RIMQHIWGAV QDKNVQPRTY ASGWLLTILR KEAHHKSHVE
HSGGVELMEK CIKKALGDAN PGVREKMRAF YWAFYAVWPA RADVIMADLD TTAQKLLIKD
PNNPNPGRKV EAPAAAARPG AGFSRSTTAV GSKPSLRETV MAQKKATLAT KNLPSRPGSA
MSTFTPSSAH SSSTQLHTTA SKPLTRHRTE TNTISVNASG MSVAPMRPVK RRPDVARPAT
AGPYSVRDQP SSREAHSPEN DQPKYTSSST SRPGGATTPK RPSSRTHISH ASESGMISPT
NIRPTGIPSP RGSPARLRHS QTMMSPTRAT DDLTLVVPTL SSIQSASPRL ESLGCSPSPI
LPAETSTSPR NEPSSRTLKV YEDPFTEDQP TPTASLHTGP VLEERAINED AANIQRPSQP
PISDDSESQD KNGQNARLLD SGITKIKAKS LEVHGFRKLQ SLIRDSRTVF TDQRFEALLI
GLFQYLEDPL PDLSADKAQD VKAQILTTIK VLLKKERRNF QPHVSRGLES LLQTRGGYDT
RAHVVSGLEL LADELVTLGN GSETAVVLTK RLQSCSDTTT EGCRTLSMGL HVLKEMLDKR
PEYVPTHKEL LQLTSMAGRC LESADSGVRM DAVKFCVALH ARVGEAAFWE AMTDIKDDPK
SLITYYIVKK QREDSIAA
//
