ID A0A0F9XDV7_TRIHA Unreviewed; 452 AA.
AC A0A0F9XDV7;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:KKO98812.1};
GN ORFNames=THAR02_09081 {ECO:0000313|EMBL:KKO98812.1};
OS Trichoderma harzianum (Hypocrea lixii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=5544 {ECO:0000313|EMBL:KKO98812.1, ECO:0000313|Proteomes:UP000034112};
RN [1] {ECO:0000313|Proteomes:UP000034112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6776 {ECO:0000313|Proteomes:UP000034112};
RX PubMed=26067977; DOI=10.1128/genomeA.00647-15;
RA Baroncelli R., Piaggeschi G., Fiorini L., Bertolini E., Zapparata A.,
RA Pe M.E., Sarrocco S., Vannacci G.;
RT "Draft whole-genome sequence of the biocontrol agent Trichoderma harzianum
RT T6776.";
RL Genome Announc. 3:E0064715-E0064715(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKO98812.1}.
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DR EMBL; JOKZ01000381; KKO98812.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F9XDV7; -.
DR OMA; WNYKFTW; -.
DR OrthoDB; 2184985at2759; -.
DR Proteomes; UP000034112; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1870.10; Domain 3, Saccharopine reductase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032095; Sacchrp_dh-like_C.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR11133:SF25; ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR Pfam; PF16653; Sacchrp_dh_C; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW Lysine biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000034112}.
FT DOMAIN 7..120
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
FT DOMAIN 124..441
FT /note="Saccharopine dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16653"
SQ SEQUENCE 452 AA; 48928 MW; FE0A4C7369FB134B CRC64;
MAPQRALLLG SGFVAKPTLD ILAEAGVEVS VACRTLEKAK KLSQGVNLAS AISLDVNDEK
ALDAAVAQHD LVISLIPYTY HAAVIKSAIR NKKHVVTTSY VSDAMMELDQ QAKDAGITVM
NEIGLDPGID HLSAVDTINN VHAAGGKILS FKSFCGGLPA PENSDNPLGY KFSWSSRGVL
LALRNAATFW EDGKIVNVAG PELMATAKPY HIYPGYAFVA YPNRDSSIYK ERYNIPEAQT
IIRGTLRYAG FPEFIKVLVD TGFLSDAEQD SFKQPIPWKE ATQKLLNAPS SSEADLVAAV
SSKTAFKDAE EKDRLISGLK WIGIFSDANI TPRGNPLDTL CATLEEKMQY EEGERDFVML
QHKFEIENKD GSRETRTSTL ADYGAPIGSG GYLSMERLVG VPAGIAAKQV LDGTLSEKGV
IAPMTAKIND PLIKELAKYG IGFKEKVIKH SA
//
